Results 221 to 230 of about 642,511 (282)

Intelligent Operator‐Independent Flexibility in Robotic Non‐Destructive Evaluation

open access: yesAdvanced Intelligent Systems, EarlyView.
Non‐destructive evaluation of high‐value components remains a manufacturing bottleneck due to rigid robotic calibration and fixturing. This study presents a flexible, adaptable system integrating 3D vision and force‐position control with a collaborative KUKA LBR robot. The geometry‐agnostic system enables pose‐independent ultrasonic inspection, detects
Amine Hifi   +11 more
wiley   +1 more source

Scalable Access to N‑Acylindole Linkages: Enabling the Synthesis of Antitrypanosomal Noncanonical Cyclic Peptides for Chagas Disease

open access: yesAngewandte Chemie, EarlyView.
A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley   +2 more sources

Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang   +7 more
wiley   +1 more source

On the Discorhabdins Leading to the Aleutianamine Ring System: A One‐Step in Situ Transformation Characterized Through Computational and Experimental Studies and Its Implications on Biosynthesis, Synthesis, and Pharmacology

open access: yesAngewandte Chemie, EarlyView.
The thiocarbenium ion rearrangement of 3‐dihydrodisorhabdin B greatly increases the recovery of aleutianamine from Latrunculia spp., a pyrroloiminoquinone natural product with potent activity against drug‐resistant cancers, collected from the deep‐ocean along the Aleutian Islands.
Cody F. Dickinson   +13 more
wiley   +2 more sources

A multi-class framework for fish species classification using deep learning technique. [PDF]

open access: yesPLoS One
Farooq Z   +5 more
europepmc   +1 more source

Correction: Taxonomic composition and functional potentials of gastrointestinal microbiota in 12 wild-stranded cetaceans. [PDF]

open access: yesFront Microbiol
Fan J   +15 more
europepmc   +1 more source

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