Results 51 to 60 of about 1,132,786 (309)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Lubricant flow analysis for effective lubrication of tractor forward/reverse clutch

Heliyon, 2017
Owing to the high power requirements of tractors, their low-power transmission gears often experience durability problems such as burning of the clutch.
Daekyung Noh, Soochul Kim, Yongjoo Kim, Joosup Jang   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Risks related to the lack of lubrication on surface integrity in drilling

Heliyon, 2019
Drilling processes can significantly affect the surface integrity of metallic components. Thus, the control of the drilling process is of great interest for industry to ensure a satisfactory surface behavior.
Mathieu Girinon, Habib Karaouni, Ugo Masciantonio, Fabien Lefebvre, Erwan Jourden, Frédéric Valiorgue, Joël Rech, Eric Feulvarch   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Effect of Single-Point Incremental Forming Process Parameters on Roughness of the Outer Surface of Conical Drawpieces from CP Titanium Sheets

Advances in Mechanical and Materials Engineering
With the widespread use of numerically controlled machine tools, single-point incremental forming (SPIF) process has enjoyed growing interest in the industry.
Marcin Szpunar, Robert Ostrowski, Department of Manufacturing and Production Engineering, Faculty of Mechanical Engineering and Aeronautics, Rzeszów University of Technology, al. Powstancow Warszawy 8, 35-959 Rzeszow, Poland   +2 more
doaj   +1 more source

Laser processing of Ti6Al4V alloy: wetting state of surface and environmental dust effects

Heliyon, 2019
Laser processing of Ti6Al4V alloy surface, via repetitive pulses, is realized incorporating the nitrogen assisting gas. The texture characteristics of the surface and wetting state are analyzed.
B.S. Yilbas, H. Ali, A. Al-Sharafi, H. Al-Qahtani   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Summary of Research 2001, Department of Mechanical Engineering [PDF]

, 2001
The view expressed in this report are those of the authors and do not reflect the official policy or position of the Department of Defense or U.S. Government.This report contains project summaries ofthe research projects in the Department ofMechanical ...
Faculty of the Department of Mechanical Engineering, Naval Postgraduate School
core  

Effect of nozzle geometry on critical-subcritical flow transitions

Heliyon, 2019
The geometry of converging-diverging nozzles affects the conditions at which critical-subcritical flow transition occurs. The objective of this work is to develop guidelines to identify the optimum nozzle geometry that maximizes critical pressure ratio ...
Jagmit Singh, Luis E. Zerpa, Benjamin Partington, Jose Gamboa   +3 more
doaj   +1 more source