Results 101 to 110 of about 13,015,703 (339)

Innovation Engineering [PDF]

, 2001
Tershak, Irina, Borshch, T.V., Zaika, L.A.   +2 more
core   +2 more sources

A Brief Course in Elementary Dynamics for Students of Engineering [PDF]

, 1909
E. G. C.
openalex   +1 more source

Multiplex Genome Engineering Using CRISPR/Cas Systems

Science, 2013
Le Cong, F. Ran, David B. T. Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, P. Hsu, Xuebing Wu, Wenyan Jiang, L. Marraffini, Feng Zhang   +10 more
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Permafrost or Permanently Frozen Ground and Related Engineering Problems

, 1948
Robert F. Black, Siemon William Muller
openalex   +2 more sources

Advances in Mechanical Engineering [PDF]

, 1909
Carl C. Thomas
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

British Chemical Engineering

, 1956

openalex   +1 more source

Engineering and Architecture [PDF]

, 1889
H J MARTEN
openalex   +1 more source

RNA-Guided Human Genome Engineering via Cas9

Science, 2013
P. Mali, Luhan Yang, K. Esvelt, John D Aach, M. Guell, James E. DiCarlo, J. Norville, G. Church   +7 more
semanticscholar   +1 more source