Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
RETRACTION: Wavelet Transform Image Enhancement Algorithm-Based Evaluation of Lung Recruitment Effect and Nursing of Acute Respiratory Distress Syndrome by Ultrasound Image. [PDF]
J Healthc EngHealthcare Engineering JO.
europepmc +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Ultrasensitive tunability of the direct bandgap of 2D InSe flakes via strain engineering
, 2018 Yang Li +11 more
openalex +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Author Correction: A flexible multi-agent system for managing demand and variability in hybrid energy systems for rural communities. [PDF]
Sci RepAli ES +6 more
europepmc +1 more source
Computing Concrete Pullout Strength [PDF]
, 1989 Beseler, Jan W., , \u2788 +1 more
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Correction: The effect of protic ionic liquid in the reduction of air contaminant gases emitted from electrical discharge machining in the presence of magnetic field. [PDF]
Sci RepKaramzadeh B +4 more
europepmc +1 more source