Results 181 to 190 of about 6,337,766 (219)
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura +10 morewiley +1 more sourceGlobal Burden of Anorexia Nervosa and Bulimia Nervosa, 1990 to 2023, With Forecasts to 2050: A Global Burden of Disease Study 2023 Analysis.
JAMA PsychiatryBai R, Dong W, Wang X, Zhang A, Santomauro DF, GBD Eating Disorders Collaborators, Aalruz H, Abiodun O, Aboagye RG, Aboshanab KM, Abreu LG, Abu Lila AS, Abukhadijah HJ, Abu-Mahfouz MS, Adamu NL, Adebiyi BO, Adekola SA, Adesina MA, Adewuyi HO, Adhanu AK, Adonteng-Kissi O, Agordoh PD, Agordoh SW, Agostinis Sobrinho C, Ahmad AMR, Ahmad K, Ahmed A, Ahmed MF, Ahmed S, Ajele KW, Akeju OO, Akinmade OV, Akosile W, Akrami AE, Al Athamneh A, Al Awaidy S, Al Maghaireh DF, Al Omari O, Al Zoubi MAM, Alam MK, Alammar MA, Al-Anzi SMF, Albashtawy M, Aldhahir AM, Alemayehu BA, Alhalabi B, Alhalaiqa FN, Alhawajreh MJ, Alhumaidi A, Ali AN, Ali MU, Alinejad Rokny H, Al-Jabi SW, Alkhatib A, Alkubati SA, Al-Marwani S, Almazan JU, Al-Raddadi RM, Alsaif B, Alsharari AF, Alshawish E, Altaany Z, Altwaijri Y, Aman Mohammadi M, Amin TT, Amugsi DA, Anil A, Anil Kumar AHS, Anjana P, Anyasodor AE, Arabi H, Aravkin AY, Areda D, Arias de la Torre J, Armocida B, Arnone D, Arruda GA, Arystan N, Ásgeirsdóttir BB, Ashraf SA, Asiamah-Asare BKY, Atoyebi SB, Atra YA, Ayala CO, Ayuso-Mateos JL, Azzam EMS, B S, Bai-Sesay AU, Balcha WF, Balhara YPS, Balmori-de-la-Miyar J, Balogun OJ, Bani Hani S, Bano F, Barker-Collo SL, Barrow A, Bashir MI, Bashir S, Bashir S, Bashiri A, Bastan MM, Batra K, Beeraka NM, Belancic A, Tune SNBK, Bhadiyadra MS, Bhaskar S, Bhattacharya S, Bisignano C, Bizzozero-Peroni B, Bodur M, Botero-Carvajal A, Breazu A, Busari AO, C S, C J S, Campos-Nonato I, Carvalho S, Castelpietra G, Cembranel F, Chadwick J, Chandika RM, Chandradasa M, Chang Y, Chen H, Choi DW, Choi YJ, Chung S, Cicero AFG, Cioffi I, Clark CCT, Cortese S, Cosentini I, Cosma C, Cruz-Martins N, Cuenca-Martínez F, Dadras O, Dagli N, Dahiya N, Dai X, Dang NB, Darunde RR, Darwesh AM, de la Torre-Luque A, Deekonda S, Derseh HA, Devnath N, Din S, Dönicke J, Dumbili EW, Durmus H, Eboreime E, Ebrahimian Sadabad F, Eddula VR, Elbarazi I, Elhoumed M, ElNahas G, Elnour AA, Elrggal ME, Metwally El-Sayed M, Eltahawy AS, Emesobum MA, Esomchi CN, Fagbamigbe AF, Fakih N, Faris ME, Faro A, Ashfaq F, Fekih-Romdhane F, Filippini T, Finnemore A, Finnemore Capon Diaz SC, Fischer F, Fogacci F, Forner Álvarez C, Fusar-Poli P, Galali Y, Ganiyu KO, Garlasco J, Gebre TS, Gerami Matin A, Getacher L, Ghafoury R, Ghamkhar A, Gharaibeh L, Ghoba S, Gholami E, Gholami Z, Gialluisi A, Giannouli V, Gilani SA, Gökulu G, Golechha M, Golmohammadi M, Gu C, Gulati S, Gutiérrez B, Habteyesus A, Hallit S, Hamarasool FO, Haq MA, Haro JM, Has EMM, Hasan T, Haslam DM, Hasnain MS, Hay SI, Hendy A, Hoek HW, Hong Y, Hoogar P, Hossain MS, Hossain SB, Hosseinzadeh M, Htay MNN, Husain W, Ibitoye SE, Ibrahim FM, Ibrahim R, Abbasi AI, Iqbal D, Iqbal M, Islam MM, Islam MS, Islam MS, Ispriantari A, Iyiola OA, Jabbarinejad R, Jacob J, Jahrami H, Jaka S, Jamal A, Jayapal SK, Jayasinghe YA, Joy GV, Jozwiak JJ, Juweid ME, K HS, Kalra S, Kang K, Kantipudi SJ, Karakasis P, Karnam RP, Kawafha MM, Khacharem A, Khader YS, Khalid S, Khalifeh AH, Khalique N, Khan AA, Khan IW, Khan MI, Khan R, Khan Z, Khasbage SU, Khezeli M, Khoshvaght P, Khotimah FH, Khubchandani J, Kieling C, Kim J, Kondlahalli SKM, Koomson I, Kotsis K, Koul A, Kuan G, Kumah E, Kumar C, Kumar M, Kumar P, Kumar R, Kumar S, Kurpas D, Kusuma D, Lajunen T, Laksono AD, Lasrado S, Latif A, Le LK, Lee HL, Lee SW, Leon-Rojas JE, Li M, Li Z, Lian Y, Liaqat A, Liu Y, Llanaj E, Lopatkina M, López-Gil JF, Luo P, Lushchak O, Lytvyak E, Ma ZF, Mahmood NH, Mahmoud IF, Malkamu B, Mary JJF, Mashudi S, Mathur N, Mattiello R, Mattoo KA, Mazzola G, Mbachu CNP, McGrath JJ, Medina JRC, Mehboob K, Mehboob R, Mehta V, Meto TM, Melariri H, Memon AR, Merlino G, Mestrovic T, Miller PA, Miller TR, Minervini G, Ming LC, Mitra T, Mohamed FI, Mohamed FAEE, Mohammed M, Mohammed Z, Moin A, Mokdad AH, Molinaro S, Monasta L, Morgan AK, Mosaddeghi-Heris R, Mostafa MS, Mughal F, Murray CJL, Muthusamy S, Myung W, Nalabothu P, Naqvi R, Nargus S, Naureen Z, Nguyen CT, Nguyen T, Nigatu YT, Niranjan V, Nkemjika S, Nnyanzi LA, Nouri M, Nzoputam CI, Nzoputam OJ, Okereke P, Olabisi OI, Olagunju AT, Olorunlana A, Ordak M, Ostojic SM, Otekunrin OA, Othman MS, Ozsahin I, Paija DM, Palma-Alvarez RF, Paramashanti BA, Pardhan S, Parikh RR, Park C, Parmar A, Patel BU, Patel M, Patil A, Patil S, Pennisi F, Pereira MO, Perna S, Pham HQ, Porntavetus T, Porru F, Porwal A, Pourghazi F, Puvvula J, Qi X, Qur'aniati N, Radojcic MR, Raggi A, Raghav YS, Rahman M, Rahmawaty S, Rajha H, Rajpoot PL, Rakhymbayev NA, Ramadan MM, Ramadhan K, Rao R, Ravi D, Rawaf S, Rehman A, Rehman W, Rizvi MR, Rolfzen ML, Romadlon DS, Ronfani L, Saddik BA, Sadeghi E, Sadek B, Saeed RF, Sagar R, Saghazadeh A, Sagoe D, Saheb Sharif-Askari N, Sahin Bodur G, Sahni V, Sahu BK, Sakshaug JW, Salaroli LB, Saleh MA, Salum GA, Sankararaman S, Saravanan A, Saylan M, Sethi Y, Shaalan Y, Shaban-Nejad A, Shaharudin S, Shahid SMA, Shahini E, Shahwan MJ, Shaikh MA, Shamim MA, Shamsutdinova A, Shan D, Sharif S, Sharifan A, Sharma G, Sharma K, Sharma S, Sheikh NA, Shetty PK, Shirali PA, Shirazi S, Shokouhifar M, Shomuyiwa DO, Siddique MKB, Siddiqui AJ, Singh A, Singh H, Singh JA, Singh J, Singh PS, Singh S, Singh V, Sridharan K, Stanculescu E, Stokes MA, Stubbs B, Sullman MJM, Sultana M, Tabarés-Seisdedos R, Tabche C, Taha ZM, Taheri N, Tampa M, Tan J, Tan KA, Tao H, Tayarani-Najaran MH, Tekola A, Temsah R, Teramoto M, Thapar R, Trabelsi K, Tran Minh Duc N, Trico D, Tromans SJ, Tsermpini E, Tufail T, Tuglo LS, Sambo AU, Vadakkethil Radhakrishnan R, Vally Z, Van Der Walt G, Vanneste S, Verma AK, Vigezzi GP, Vikram V, Almeida von Humboldt S, Wang S, Wang X, Wang Y, Wickramasinghe ND, Williams F, Wirtu GK, Wonde TE, Yamada N, Yang H, Yano Y, Yergaliyev KA, Yesodharan R, Yismaw YE, Yon DK, Yonemoto N, Zafar MS, Zamagni G, Zarea K, Zargar S, Zastrozhin M, Zawiah M, Zeru EM, Zhang Z, Zyoud SH. +504 moreeuropepmc +1 more sourceUSP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie +8 morewiley +1 more sourceTumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann +9 morewiley +1 more sourceAttitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme +7 morewiley +1 more source
