Results 131 to 140 of about 4,725,711 (307)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

FEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Homogeneous polymer-ionic solvate electrolyte with weak dipole-dipole interaction enabling long cycling pouch lithium metal battery

Nature Communications
Solid polymer electrolytes (SPEs) are considered as promising electrolytes for high-voltage lithium metal batteries. Whereas, the strong dipole-dipole interaction in polymer electrolytes limits the enhancement of the ionic conductivity.
Likun Chen, Tian Gu, Jinshuo Mi, Yuhang Li, Ke Yang, Jiabin Ma, Xufei An, Yuyuan Jiang, Danfeng Zhang, Xing Cheng, Shaoke Guo, Zhuo Han, Tingzheng Hou, Yidan Cao, Ming Liu, Wei Lv, Yan-Bing He, Feiyu Kang   +17 more
doaj   +1 more source

Modeling of aneurysm progression in anterior cerebral arteries to estimate rupture risk: A computational study

Biomedical Engineering Advances, 2023
A cerebral aneurysm is a medical disorder that occurs when the wall of the cerebral artery ruptures as a result of abnormally high blood pressure.
Gurpreet Singh, Prem Nath Yadav, Shubham Gupta, Arnab Chanda   +3 more
doaj  

Carnot's theorem and Szilárd engine [PDF]

arXiv, 2016
In this work, the relationship between Carnot engine and Szil\'ard engine was discussed. By defining the available information about the temperature difference between two heat reservoirs, the Carnot engine was found to have a same physical essence with Szil\'ard engine: lossless conversion of available information. Thus, a generalized Carnot's theorem
arxiv  

Developing an undergraduate software engineering degree [PDF]

, 2003
As those who have done it can attest, developing an undergraduate degree in software engineering is a daunting and challenging task, and there have been instances where a department has tried, but failed to get its program approved.
Armarego, J., Bagert, D.J., Eisenbach, S., Hilburn, T.B., Naveda, J.F., Seidman, S.   +5 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

RICE for All Aspects of Chemical Engineering

Recent Innovations in Chemical Engineering (Formerly Recent Patents on Chemical Engineering), 2019

openaire   +2 more sources

2007 ASME International Design Engineering Technical Conferences (IDETC2007) September 4–7, 2007 Rio All-Suite Hotel & Casino, Las Vegas, Nevada, USA [PDF]

, 2006
H. S. Tzou, Nader Jalili
openalex   +1 more source