Results 131 to 140 of about 1,989,992 (317)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Engineering Identity and Attitudes to Engineering Professional Practice: A Pilot Study
CONTEXT Engineering identity has become an area of research interest when considering how to improve the student experience within engineering. Students build their engineering identity during their studies by seeing themselves as engineers, aligning ...
Hall, Wayne +2 more
core
Conference Modern Engineering : Science and Education
, 2017 This book draws together the most interesting recent results to emerge in mechanical engineering in Russia, providing a fascinating overview of the state of the art in the field in that country which will be of interest to a wide readership.
Evgrafov, Alexander
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
, 2004 Why consider opposing viewpoints? -- Introduction -- Ch. 1. How will genetic engineering affect society? -- Chapter preface -- 1. Genetic engineering benefits society / Henry I. Miller and Gregory Conko -- 2.
Gerdes, Louise I., ed.
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
ELECTRIC VEHICLE POWERTRAIN DESIGN: INNOVATIONS IN ELECTRICAL ENGINEERING
The electrification of vehicles is reshaping transportation, with electric vehicle (EV) powertrain design playing a key role in this shift. This review focuses on recent innovations in electrical engineering that have enhanced EV powertrains ...
Hossain, MD Shakhawat +4 more
core
An introduction to mechanical engineering
, 2010 An Introduction to Mechanical Engineering: Part 2 is an essential text for all second-year undergraduate students as well as those studying foundation degrees and HNDs.
Clifford, Michael
core
THE STRUCTURE OF YIELD OF RICE BREEDING SAMPLES AND ITS EFFECT ON PRODUCTIVITY
Зерновое хозяйство России, 2018 The article gives the results of the structural analysis of the productivity of rice breeding samples from control seed-plot during the years of 2012-2014.
P. I. Kostylev +4 more
doaj