Results 231 to 240 of about 20,798,907 (307)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Reshaping the landscape of HLA desensitization through immune engineering. [PDF]

Transpl Int
Kervella D, Bestard O.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

RETRACTED: Prażnowski et al. Assessment of the Road Surface Condition with Longitudinal Acceleration Signal of the Car Body. <i>Sensors</i> 2020, <i>20</i>, 5987. [PDF]

Sensors (Basel)
Prażnowski K, Mamala J, Śmieja M, Kupina M.   +3 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Strengthening biomedical engineering systems in sub-Saharan Africa: a repeated cross-sectional assessment of workshop readiness and medical device maintenance in NEST360-supported hospitals. [PDF]

J Glob Health
Wainaina J, Bohne CA, Banda G, Ochieng V, Osuagwu C, Ngowi E, Peter HD, Jenkins G, Madete J, Alooh M, Nambiar A, Liaghati S, Ogero M, Penzias RE, Kumara D, Hirschhorn LR, Oden ZM, Richards-Kortum R, NEST360 Health Facility Assessment Collaborative Group.   +18 more
europepmc   +1 more source

Engineering Framework for Intelligent Vision Inspection Systems (EF-IVIS): A Systems Engineering Methodology. [PDF]

Sensors (Basel)
Rysiński J, Jancarczyk D.
europepmc   +1 more source

Correction: Predictive fatigue-aware human-robot collaboration: a real-time, open-source ROS 2 instantiation of a three-module human-centric digital twin framework on a standard cobot. [PDF]

Front Robot AI
Goonetilleke RP, Khalid A.
europepmc   +1 more source