Results 291 to 300 of about 24,595,607 (343)

It’s All About Engagement: Infusing the Mobile Studio Approach Throughout the Electrical Engineering Curriculum [PDF]

Steven S. Holland, Jennifer L. Bonniwell, Joshua Carl, Brian Faulkner, Richard Kelnhofer, Cory J. Prust, Luke Weber   +6 more
openalex   +1 more source

Patient Triage and Guidance in Emergency Departments Using Large Language Models: Multimetric Study.

J Med Internet Res
Wang C, Wang F, Li S, Ren QW, Tan X, Fu Y, Liu D, Qian G, Cao Y, Yin R, Li K.   +10 more
europepmc   +1 more source

Fast and accurate Bayesian optimization with pre-trained transformers for constrained engineering problems. [PDF]

Struct Multidiscipl Optim
Yu RT, Picard C, Ahmed F.
europepmc   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Correction: Xing et al. Enhancing the Stability of Litsea Cubeba Essential Oil Emulsions Through Glycosylation of Fish Skin Gelatin via Dry Maillard Reaction. <i>Foods</i> 2024, <i>13</i>, 3847. [PDF]

Foods
Xing N, Tang S, Wang X, Guo C, Hu X, Yi J.   +5 more
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Correction: Khort et al. Automated Mobile Hot Mist Generator: A Quest for Effectiveness in Fruit Horticulture. <i>Sensors</i> 2022, <i>22</i>, 3164. [PDF]

Sensors (Basel)
Khort D, Kutyrev A, Kiktev N, Hutsol T, Glowacki S, Kuboń M, Nurek T, Rud A, Gródek-Szostak Z.   +8 more
europepmc   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Structural Homology Fails to Predict Secretion Efficiency in <i>Pichia pastoris</i>: Divergent Responses of Architecturally Similar scFvs to Multi-Parametric Genetic Engineering. [PDF]

Int J Mol Sci
Wang N, Xiao Y, Liu X, Li Y, Yu D, Guo J, Lu P, Zhang X.   +7 more
europepmc   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source