Results 111 to 120 of about 5,500,511 (357)

Incentive Regulation and the Role of Convexity in Benchmarking Electricity Distribution: Economists versus Engineers [PDF]

This note illustrates the potential impact of the specification of a convex production technology on establishing minimal costs compared to the use of a non-convex technology when benchmarking electricity distributors.
Emili Grifell-Tatjé, Kristiaan Kerstens
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

TECHNOLOGY OF OPEN-ENDED ENGINEERING IN TRAINING OF ENGINEERS

Высшее образование в России, 2017
The article presents the authors’ technology of interdisciplinary open-ended engineering. This technology is an integrated teaching method that significantly increases the practical component in the educational program.
A. P. ISAEV, L. V. PLOTNIKOV, N. I. FOMIN   +2 more
doaj  

Effect of Boundary Conditions in Segmental Lining Model on its Sectional Force [PDF]

, 2016
Chaiyaput, S., Graduate student, Department of Civil and Environmental Engineering, Nagaoka University of Technology, Professor, Department of Civil and Environmental Engineering, Nagaoka University of Technology, Sugimoto, M.   +3 more
core   +1 more source

Middle school students' perceptions of engineering [PDF]

, 2011
This paper focuses on implementing engineering education in middle school classrooms (grade levels 7-9). One of the aims of the study was to foster students’ and teachers’ knowledge and understanding of engineering in society.
Dawes, Les, English, Lyn, Hudson, Peter
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Fighter aircraft flight control technology design requirements [PDF]

, 1984
The evolution of fighter aircraft flight control technology is briefly surveyed. Systems engineering, battle damage considerations for adaptive flutter suppression, in-flight simulation, and artificial intelligence are briefly ...
Nelson, W. E., Jr.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

0305 Rationality and Progress versus Natural Creative Talent

RIHA Journal
The paper focuses on the gendered self-conceptions of engineers and their relevance for studying world exhibitions. It thus analyses debates in German engineering around 1900 on the relationship between technology and culture in order to reconstruct how ...
Tanja Paulitz
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source