Results 181 to 190 of about 4,234,556 (345)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Engineering application and optimization of a synergistic air curtain-wet vortex dust control system at continuous miner faces. [PDF]

Sci Rep
Wang J, Hu S, Zhang X, Yuan Z, Deng H, Du J, Jin K, Zhou W, Wang H, Zhang K.   +9 more
europepmc   +1 more source

Seismic Performance and Engineering Application Investigation of a New Alternative Retainer. [PDF]

Polymers (Basel), 2022
Yan L, Li G, Gou X, Zhang P, Wang X, Jiang Y.   +5 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Nanohydroxyapatite and its composite scaffold for bone tissue engineering application: a systematic review. [PDF]

J Mater Sci Mater Med
Shendage S, Chan YS, Chang JY, Ghule AV.
europepmc   +1 more source

Extraction of Hydroxyapatite from Camel Bone for Bone Tissue Engineering Application. [PDF]

Molecules, 2022
Khurshid Z, Alfarhan MF, Mazher J, Bayan Y, Cooper PR, Dias GJ, Adanir N, Ratnayake J.   +7 more
europepmc   +1 more source

Formalization of System Engineering Processes (Proposal of a method to adapt generic processes to different application contexts)

, 2007
Samuel Rochet, BARON, Claude
openalex   +1 more source

Interfacially Coupled Bi2WO6@WS2-PVDF Based Membranes for Sonophotocatalytic Trimethoprim Removal: From Material Engineering to Surface- and Groundwater Applications

Gluchowski, Pawel, Czekanowska, Dominika
openalex   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Experimental study and engineering application of bolt support based on large-scale sliding coal bump in coal body. [PDF]

Sci Rep
Wang C, Ma S.
europepmc   +1 more source