Results 171 to 180 of about 1,537,042 (315)
Experimental study on mechanical response of soft soil freezing in underground excavation using artificial ground freezing method. [PDF]
Han L, Yi L, Zhang P, Chai L, Cheng Z.
europepmc +1 more source
Control Engineering Practice [PDF]
Control Engineering Practice strives to meet the needs of industrial practitioners and industrially related academics and researchers. It publishes papers which illustrate the direct application of control theory and its supporting tools in all possible ...
CASTALDI, PAOLO
core
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Journal of Control Science and Engineering
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Journal of Control Science and Engineering
doaj +1 more source
Biomimetics as a Functional Engineering Framework for Mechanical Systems: A PRISMA-Guided Systematic Mapping of Sensing, Inspection, Access Robotics, and Condition Monitoring (2016-2026). [PDF]
Ketterer CG, Ortega NN, Valín JL.
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Journal of Control Science and Engineering
doaj +1 more source
A Systematic Taxonomy of the Sunflower Optimization Algorithm: Variants, Hybridization Strategies, Applications, and Research Directions. [PDF]
Baştemur Kaya C.
europepmc +1 more source

