RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Intersubjective management in aerospace engineering
This article presents a postnonclassical approach to create the science of management processes organization in a developing society, the focus of which is “the man of culture”, i.e.
Arpentieva Mariam +2 more
doaj +1 more source
Research on the Intelligent Construction and Development of Bridge Engineering Safety Management [PDF]
To deeply explore the development path of intelligent construction of bridge engineering safety management under the background of intelligent construction in China’s construction industry, based on the technical characteristics of bridge engineering and
Zhang Siyuan, Yu Bo, Li Ruipu, Wan Yang
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Town of New Durham Stormwater Management & Erosion Control Project [PDF]
Appledore Engineering worked with the New Durham Planning Board to develop a stormwater management and erosion control ordinance and to adopt complimentary improvements to the town’s site plan review and subdivision ...
Town of Durham
core +2 more sources
Boundary Objects and their Use in Agile Systems Engineering
Agile methods are increasingly introduced in automotive companies in the attempt to become more efficient and flexible in the system development. The adoption of agile practices influences communication between stakeholders, but also makes companies ...
Knauss, Eric +3 more
core +1 more source
Resource integration and dynamic capability of frontline employee during COVID-19 pandemic: From value creation and engineering management perspectives. [PDF]
Chatterjee S +4 more
europepmc +1 more source
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Prototype of a new Engineering Masters project model: Working with marketing and software faculties to commercially kickstart university research [PDF]
We describe a Master of Engineering (500-level) project modelled on the real-world arrangement where engineers work with marketing and software groups to prepare a product for commercialisation.
Barr-Smith, Anthony +7 more
core +1 more source
A conceptual management model for the creation of an innovate engineering product
The purpose of the research is to develop a conceptual model of innovation management in the creation of an innovative engineering product. Research object: innovative engineering.
I. S. Mukhin
doaj +1 more source

