Results 151 to 160 of about 11,840,051 (392)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Extensible Generic Data Management Software [PDF]

arXiv, 2013
Extensibility mechanisms constitute a form of knowledge capture that is essential for software re-use. The Data Intensive Cyber Environments (DICE) group has collaborated with twenty-five science and engineering domains on the application of the iRODS policy-based data management system.
arxiv  

Closure to “Discussion of ‘Practices in Operational Management—Engineering Management’” (1961, ASME J. Eng. Ind., 83, pp. 306–307) [PDF]

, 1961
C. E. Paules
openalex   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Analysis of the Relationship Between Engineering Project Management and Engineering Product Development: A Review

Journal of Studies in Civil Engineering
This study explores the two distinct parts of engineering management: engineering product management and engineering project management. A qualitative systematic review method was employed, using purposively sampled literature and a desk-based research ...
Lynda Chinwendu Mbadugha, Franklin Arinze Ikeotuonye, Ikenna Emmanuel Idoko   +2 more
doaj   +1 more source

The role of innovation for economy and sustainability of photovoltaic modules

iScience, 2022
Summary: The role of innovation for the success of photovoltaics cannot be overstated. Photovoltaics have enjoyed the most substantial price learning of any energy technology. Innovation affects photovoltaic performance in more ways, though.
Ian Marius Peters, Jens A. Hauch, Christoph J. Brabec   +2 more
doaj  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays

FEBS Open Bio, Volume 15, Issue 5, Page 690-698, May 2025.
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques, Edit Ábrahám, Hiromi Muramatsu, Daniel Youssef Bargieri, Norbert Pardi, Zoltán Lipinszki   +5 more
wiley   +1 more source

When it comes to the chemical process industries, Management in Depth reads Chemical and Engineering News. [PDF]

, 1967

openalex   +1 more source

University of Central Florida 1985 Self Study Southern Association of Colleges and Schools: Department of Industrial Engineering and Management Systems Self Study [PDF]

, 1985
University of Central Florida Department of Industrial Engineering and Management Systems 1985 Self Study for Southern Association of Colleges and Schools.
University of Central Florida. Department of Industrial Engineering and Management Systems
core   +1 more source