Results 61 to 70 of about 689,327 (298)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Engineering Education in India: Preparation of Professional Engineering Educators

Journal of Human Resource and Sustainability Studies, 2016
In 21st century, engineering education in India faces significant challenges as it requires meeting the demands of technical profession and emerging job market. Researchers have found some universally preferred, yet challenging skills for global workforce, e.g., science, technology, engineering and math (STEM), statistics and data analysis skills, are ...
Atasi Mohanty, Deepshikha Dash
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Study on particle fluidization characteristics and separation effect of coarse slime fluidized flotation

Meitan kexue jishu
The new gas-liquid-solid fluidized bed flotation technology can realize the efficiency recovery of coarse particles based on the principle of refloating coupling.
Qinglin YIN, Shihao DING, Yiqing ZHANG, Qi HE, Yaowen XING, Xiahui GUI   +5 more
doaj   +1 more source

Constituents and Anti-Hyperuricemia Mechanism of Traditional Chinese Herbal Formulae Erding Granule

Molecules, 2019
Erding granule (EDG) is a traditional Chinese medicine that has recently been identified as having anti-hypouricemic effects. However, the active components and underlying mechanism for this new indication have not been elucidated. Therefore, we compared
Wugang Zhang, Wendi Du, Guofeng Li, Chen Zhang, Wuliang Yang, Shilin Yang, Yulin Feng, Haifang Chen   +7 more
doaj   +1 more source

Preparation of Entangled States through Hilbert Space Engineering

Physical Review Letters, 2016
44 pages, 10 ...
Lin, Y., Gaebler, J. P., Reiter, F., Tan, T. R., Bowler, R., Wan, Y., Keith, A., Knill, E., Glancy, S., Coakley, K., Sorensen, A. S., Leibfried, D., Wineland, D. J.   +12 more
openaire   +5 more sources

Social Engineering Attack Awareness and Preparation Training Program Design: A Case study [PDF]

, 2023
Eric Blancaflor, Alexandra Mikaela, G Celestial, Jezel Gonzales, Emmanuel Carlos   +4 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Construction and optimization of a genetic transformation system for efficient expression of human insulin-GFP fusion gene in flax

Bioresources and Bioprocessing
The human insulin gene modified with a C-peptide was synthesized according to the plant-preferred codon, and a fusion gene expression vector of insulin combined with green fluorescent protein (GFP) was constructed.
Wei Zhao, Rui Zhang, Luyang Zhou, Zhongxia Zhang, Fei Du, Ruoyu Wu, Jing Kong, Shengjun An   +7 more
doaj   +1 more source

Latifolin protects against myocardial infarction by alleviating myocardial inflammatory via the HIF-1α/NF-κB/IL-6 pathway

Pharmaceutical Biology, 2020
Context The Traditional Chinese herb medicine Dalbergia odorifera T. Chen (Fabaceae), exerted a protective effect on myocardial ischaemia. Latifolin is a neoflavonoid extracted from Dalbergia odorifera.
Xiao-Xiao Lai, Ni Zhang, Lan-Ying Chen, Ying-Ying Luo, Bin-Yao Shou, Xin-Xu Xie, Rong-Hua Liu   +6 more
doaj   +1 more source