Results 151 to 160 of about 1,196,222 (318)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Polylactide microcapsules and films: preparation and properties

, 2009
This thesis aims at preparation of hollow polylactide (PLA) microcapsules for use as ultrasound contrast agents with controlled size, structure and mechanical and thermal properties.
Sawalha, H.I.M.
core  

Structural integrity of engineering components made of functionally graded materials [PDF]

, 2008
Functionally graded materials (FGM) are composite materials with microstructure gradation optimized for the functioning of engineering components. For the case of fibrous composites, the fibre density is varied spatially, leading to variable material ...
Oyekoya, Oyedele O.
core  

Predicting the Engineering Properties of Rocks from Textural Characteristics Using Some Soft Computing Approaches. [PDF]

Materials (Basel), 2022
Fereidooni D, Sousa L.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Engineering Properties of PVA Fibre-Reinforced Geopolymer Mortar Containing Waste Oyster Shells. [PDF]

Materials (Basel), 2022
Deng Z, Yang Z, Bian J, Pan X, Wu G, Guo F, Fu R, Yan H, Deng Z, Chen S.   +9 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Improvements in the Engineering Properties of Cementitious Composites Using Nano-Sized Cement and Nano-Sized Additives. [PDF]

Materials (Basel), 2022
Rahman I, Singh P, Dev N, Arif M, Yusufi FNK, Azam A, Alam MM, Singh S, Chohan JS, Kumar R, Sharma L, Tag-Eldin E, Sharma S, Asyraf MRM.   +13 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Influence of material composition on the morphology and engineering properties of waste plastic binder composite for construction purposes. [PDF]

Heliyon, 2022
Babatunde Y, Mwero J, Mutuku R, Jimoh Y, Oguntayo D.   +4 more
europepmc   +1 more source