Results 121 to 130 of about 4,282,224 (344)

Guest Editorial ... Ethical Issues in Community and Research Medicine [PDF]

open access: yes, 1971
The following guest editorial by Saltonstall Professor of Population Ethics, Arthur J. Dyck, is reprinted from the New England Journal of Medicine. In it reference is made to an article, Ethics of a Cottage Industry in an Age of Community and Research ...
Dyck, Arthur J.
core   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐modifying Antirheumatic Drug

open access: yesArthritis Care &Research, Accepted Article.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD) Methods PrismRA incorporated 19 gene expression features and 4 clinical features to assess a patient's likelihood of ...
Fenglong Xie   +3 more
wiley   +1 more source

The Business Consortium Fund: working capital for MBEs [PDF]

open access: yes
The New England Minority Purchasing Council offers minority business enterprises (MBEs) help in obtaining short-term working capital.Commercial loans - New England ; Small business - New England ; Minority business enterprises - New ...
Marques Benton
core  

Information-theoretic bound on the entropy production to maintain a classical nonequilibrium distribution using ancillary control

open access: yes, 2017
There are many functional contexts where it is desirable to maintain a mesoscopic system in a nonequilibrium state. However, such control requires an inherent energy dissipation.
England, Jeremy L., Horowitz, Jordan M.
core   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Tuning the Dielectric Properties of Individual Clay Nanosheets by Interlayer Composition: Toward Nano‐Electret Materials

open access: yesAdvanced Functional Materials, EarlyView.
The dielectric properties of clays are studied on the level of individual monolayers and functional double stacks. The material breakdown characteristics and charge storage performance are analyzed. For illustration, a defined charge pattern representing a cuneiform character is produced, written into a microscopic clay tile, referencing the origins of
Sebastian Gödrich   +6 more
wiley   +1 more source

New England migration trends [PDF]

open access: yes
Recent studies and reports have called attention to the issue of population migration patterns in New England. To provide more targeted and regional data on this issue, NEPPC has developed a series of findings and maps that, for the first time, present a
David Agrawal
core  

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