Results 141 to 150 of about 916,988 (245)

Identifying innovative models of urgent care in rural coastal areas in England: the Elevate study - a mixed-methods protocol. [PDF]

BMJ Open
Lampard P, Adamson J, Anderson H, Ballantine L, Bell F, Benger JR, Blakey RL, Dickinson P, Dykes S, Gaughan J, Maitland-Knibb S, Mensah D, Ransome ZA, Richardson G, Santos R, Sheridan R, Sivey P, Smith E, Song W, Sutcliffe M, Stockwell CJ, Voss S, Scantlebury A.   +22 more
europepmc   +1 more source

AI‐Enhanced Vibrational Capsule for Minimally Invasive Detection of Abnormal Bowel Tissue

Advanced Science, EarlyView.
A fully integrated vibration‐assisted capsule is presented for the minimally invasive detection of bowel lesions. The capsule incorporates a wireless sensor and an eccentric motor to probe tissue mechanics in situ. By coupling triaxial vibration signals with AI‐based classification and analytical modeling, the system enables early, non‐visual ...
Xizheng Fang, Yao Yan, Kenneth Omokhagbo Afebu, Andrew Bickerdike, Bo Tian, Yang Liu, Shyam Prasad   +6 more
wiley   +1 more source

A national benchmarking survey to explore the use of dose error reduction software in adult intensive care units (ICUs). [PDF]

J Intensive Care Soc
Morgan S, Lamont S.
europepmc   +1 more source

ENGLAND: March and April were the Cruellest Months

Critical Stages, 2020
John Causebrook, John Elsom
doaj  

Sensory Nerve‐Derived CGRP Controls Osteoclastogenesis by Limiting Macrophage Bioenergetics in Bone Repair

Advanced Science, EarlyView.
Sensory nerves help bones heal. This study shows that the neuropeptide CGRP, released from sensory nerves, slows down macrophage energy production, preventing excessive bone breakdown. By revealing this nerve–immune–metabolism connection, the work provides new insight into how the body balances bone repair and opens doors to targeted treatments ...
Jiaying Liu, Ting Zhang, Yuqing Mu, Lili Li, Ju Jin, Kevin J Dudley, Wendong Gao, Donglin Cai, Fuhua Yan, Lan Xiao, Yin Xiao   +10 more
wiley   +1 more source

Book Reviews, Part 2

Scottish Studies, 1966
J. MacQueen A. Fenton
doaj  

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

Advanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang, Jingrui Wang, Qiaowan Chen, Chen Jiao, Yun Chen, Zhongshou Wu, Zhonghua Ma   +6 more
wiley   +1 more source

Outpatient hospital attendances in people with rheumatoid arthritis during the COVID-19 pandemic and beyond: a cohort study in three nations of the UK. [PDF]

Rheumatology (Oxford)
Costello RE, Parker M, Kennedy J, Brophy S, Mehrkar A, Bacon S, Goldacre B, MacKenna B, Evans D, Tomlinson LA, Hollick RJ, Humphreys JH, OpenSAFELY Collective, The RHEUMAPS Study Investigators and the LH&W NCS (or CONVALESCENCE) Collaborative .   +13 more
europepmc   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Estimating influenza A subtype ratios among critical care admissions in England. [PDF]

Epidemiol Infect
Wolmuth-Gordon HS, Elgohari S, Dabrera G, Green RE.   +3 more
europepmc   +1 more source