Results 301 to 310 of about 4,724,242 (392)

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source

Trends in childhood obesity for upper tier local authorities in England between 2007/08 and 2023/24: a latent trajectory analysis. [PDF]

J Public Health (Oxf)
Rahilly J, Cortina-Borja M, Mytton O.
europepmc   +1 more source

Blood pressure and adverse cardiovascular outcomes in older people with type 2 diabetes and chronic kidney disease: Findings based on the Clinical Practice Research Datalink databases in England [PDF]

Anna Meffen, Freya Tyrer, Junior Mbah Mbahnjeck, Kamlesh Khunti, Francesco Zaccardi, Setor K. Kunutsor   +5 more
openalex   +1 more source

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo   +9 more
wiley   +1 more source

Trends in Paediatric surgerical volume and associated mortality in England: a nationwide study over an eight year period. [PDF]

BJA Open
Althonayan J, Fowler AJ, Allin B, Sogbodjor A, Bradnock T, Orban N, Dobbs TD, Knight M, Pearse RM, Abbott TEF.   +9 more
europepmc   +1 more source

Microglial Rack1 Deficiency Alleviates Alzheimer's Disease Pathology through Enhancing IGF1‐Mediated Astrocytic Phagocytosis

Advanced Science, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang, Yanling He, Pin Yang, Hengchang Zhang, Yueyang Tong, Lingling Jiang, Zehan Li, Meichen Yan, Xiaoheng Li, Qinghu Yang, Jing Yang, Zengqiang Yuan, Jiyan Zhang, Jinbo Cheng   +13 more
wiley   +1 more source

Assessing AI-Generated Autism Information for Healthcare Use: A Cross-Linguistic and Cross-Geographic Evaluation of ChatGPT, Gemini, and Copilot. [PDF]

Healthcare (Basel)
Rakap S, Gulboy E, Bayrakdar U, Cure G, Besdere B, Aydin B.   +5 more
europepmc   +1 more source

SLPI⁺ AT2‐Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche

Advanced Science, EarlyView.
Integrating spatial transcriptomics and single‐cell RNA sequencing, this study identifies a novel subpopulation of SLPI⁺ AT2‐like cells at the invasive margin of lung adenocarcinoma (LUAD). These cells, through stromal crosstalk and Wnt pathway activation, promote tumor stemness and invasion.
Zhoufeng Wang, Guonian Zhu, Pan Tang, Yan Wang, Wenxin Luo, Wenpeng Song, Zhikang Pan, Bingjie Zheng, YongChao Jiang, Defu Xiao, Xin Jin, Yong Bai, Guowei Che, Weimin Li   +13 more
wiley   +1 more source

Hydrogel‐Coated Foam Evaporator Achieving Four‐In‐One Benefits for Efficient and Stable Solar‐Driven Water Purification

Advanced Science, EarlyView.
This study introduces a universal strategy for foam‐based solar evaporators, leveraging the unique advantages of hydrogel materials to effectively reduce evaporation enthalpy. At the same time, it addresses challenges such as the need for pore formation in hydrogels, water‐induced swelling, and the detachment of photothermal materials, achieving “four ...
Lele Li, Yanhong Dong, Shu Liu, Xingmin Du, Diandian Yu, Jie Wen, Chenxi Wang, Qian Sun, Bing Liu, Tao Wu, Jiahui Yu   +10 more
wiley   +1 more source

Are Artificial Intelligence-generated Patient Leaflets Ready for Clinical Use? A Readability Comparison across Common Orthopaedic Procedures. [PDF]

J Orthop Case Rep
Jido JT, Wizni AA.
europepmc   +1 more source