Results 41 to 50 of about 1,080,903 (314)
England is the World and the World is England [PDF]
postmedieval, 2018 Medieval Christians arguably lived in a ‘real’ world – a tangible place in which they lived, worked, loved, hated, and died – but through a process of world-building continually reconstructed it anew around themselves as the mythical land they called ‘Christendom.’ This was predicated first on reconceptualizing and then ultimately on removing (or ...
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Satires in Julian Barnes’s England, England
Cognizance Journal of Multidisciplinary Studies, 2023 This paper conducts a study on the implication of satires in Julian Barnes’s novel England, England. The purpose of this study is to make an in-depth analysis of the tendency of contemporary British people more specially the businessmen who try to misrepresent the actual England for their own purposes and how artistically Julian Barnes is successful to
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Crenosoma vulpis infection in a four-month old puppy
Helminthologia, 2016 Here we report the case of a diagnostic and treatment challenge in a four-month old dog from England, presented with one-month history of unproductive cough. Antigen blood test for Angiostrongylus vasorum infection was negative.
Matos B. +5 more
doaj +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Love-led practice in children's residential care
Scottish Journal of Residential Child Care, 2023 The author describes a small-scale project, called Lovin' Care, designed to facilitate love-led practice in children's residential care in England.
Margaret Davies
doaj +1 more source