Results 41 to 50 of about 12,504,073 (316)
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Middle English: English or Frenglish?
The article focuses on a general description of Middle English considering the impact ofthe French language on its development during this period. Despite an extensive number of Frenchborrowings in different layers of the English language, the language remained English and itspredominant features were still those of Germanic origin
Ikalyuk, L.M., Tatsakovych, U.T.
openaire +3 more sources
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
English Lecturer's Attitude Toward English Variety In English Learning
This research investigates English lecturers' attitude toward the variation of English in the process of English learning. The purpose of this study is to discuss the types of English variations uttered by English lecturers who are considered as respondents in this study and their attitudes toward the variations of language that appear to their own ...
Yanti, Rahma +2 more
openaire +4 more sources
The Shelley-Godwin Archive: The edition of Mary Shelley’s Frankenstein Notebooks
The Shelley-Godwin Archive aims to bring the widely scattered handwritten legacy of the Shelley-Godwin family together on one platform. To date, in October 2014, it is still in the beta phase.
Frederike Neuber
doaj +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
The Educational and Psychological Need for Learning the English Language and Understanding the Different Anxieties [PDF]
Balachandran Vadivel +3 more
openalex +1 more source
Review of “ShakespearePlaysPlus Text Corpus”
ShakespearePlaysPlus is a freely available digital text corpus of William Shakespeare’s plays. The 37 plays were compiled from the Oxford University Press 1916 Edition of “The Complete Works of William Shakespeare” and annotated by Mike Scott for his own
Katharina Mahler
doaj +1 more source

