Results 161 to 170 of about 2,254,396 (294)

Acceptance of evolution theory and understanding of human evolution among health sciences students in France: A national cross‐sectional study

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Evolutionary theory provides a fundamental framework for understanding human anatomy and health. However, evolution acceptance and conceptual understanding are distinct constructs that may not co‐vary. This study aimed to assess (1) evolution acceptance and (2) knowledge of human evolution in health sciences students.
Thomas Colard   +4 more
wiley   +1 more source

Affective dimensions in the information behavior of forcibly displaced people: A literature review. An Annual Review of Information Science and Technology (ARIST) paper

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract This review analyzed 241 scholarly articles published between 2010 and 2025 in information science venues to examine how affect shapes refugees' information behavior during forced migration and to identify additional contextual factors. It identifies seven affective dimensions: anxiety, shame and stigma, grief and loss, frustration, (mis)trust,
Maja Krtalić, Lilach Alon
wiley   +1 more source

Predictors of Change in Severity of Self‐Injurious Behaviors in Preschool‐Aged Autistic Children

open access: yesAutism Research, EarlyView.
ABSTRACT Self‐injurious behaviors (SIBs) affect up to 50% of autistic individuals and significantly impact quality of life and everyday functioning. Cross‐sectional studies link the presence of SIB to lower IQ, altered sensory responsivity, and poor emotion regulation, yet their effect on changes in SIB severity from early childhood to school age in ...
Joseph Boyle   +9 more
wiley   +1 more source

Recent Non‐Suicidal Self‐Injury in Autistic Adolescents and Adults: Characteristics, Clinical Correlates and Suicidal Thoughts and Behaviors

open access: yesAutism Research, EarlyView.
ABSTRACT Non‐suicidal self‐injury (NSSI) is prevalent among autistic adolescents and adults, yet research on its clinical characteristics, functions, and association with suicidal thoughts and behaviors (STBs) in this population remains limited. This study compared these domains between autistic adolescents and adults with and without recent NSSI.
Safaa Eldeeb   +7 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra   +8 more
wiley   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

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