Results 41 to 50 of about 156,905 (248)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Transcutaneous electrical acupoint stimulation promotes general anesthesia recovery in patients undergoing gastrointestinal surgery

针刺研究, 2021
Objective To observe the effect of transcutaneous electrical acupoint stimulation(TEAS) on the recovery of patients undergoing gastrointestinal surgery under general anesthesia.
TIAN Wei-qian, HU Cheng, YANG Guang
doaj   +2 more sources

Effects of Implementing an Enhanced Recovery after Surgery pathway on Hysterectomy Postoperative Outcomes [PDF]

Egyptian Journal of Health Care
Background: The implementation of an Enhanced Recovery after Surgery (ERAS) pathway for women undergoing hysterectomy represents a rigorously evidence-based strategy aimed at improving postoperative outcomes, mitigating complications, facilitating ...
Nehal Shalaby Awad Mahmoud, Hanan Abdelrahman Mostafa Kandeel, Samar Elrefaey Elrefaey Abaza   +2 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

PRF Membranes Enhance Postoperative Recovery After Periapical Surgery: A Single-Blind Randomized Pilot Trial Using 3D Imaging

Oral
Background: Periapical surgery is indicated for persistent periapical lesions that do not respond to conventional endodontic therapy, yet postoperative recovery is often hindered by pain, swelling, and delayed healing.
Martin Major, Melinda Polyák, Tamás Würsching, Gábor Kammerhofer, Éva Kocsis, Zsolt Németh, György Szabó   +6 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Revolutionizing perioperative medicine: Technological advancements for enhanced recovery [PDF]

Serbian Journal of Anesthesia and Intensive Therapy
Enhanced Recovery After Surgery (ERAS) is a multimodal, evidence-based approach designed to minimize surgical stress, accelerate recovery, and improve patient outcomes.
Bharadwaj Abhishek
doaj   +1 more source

The benefits of enhanced recovery after surgery

Journal of Visceral Surgery, 2016
Enhanced recovery programs (ERP) after surgery are now being increasingly applied in daily practice. The purpose of this article is to review specific aspects and advantages of this approach. Beyond the reduction in overall morbidity (found for multiple surgical specialties), ERP include issues and stakes that affect patient care, the care team and ...
openaire   +2 more sources

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source