Results 41 to 50 of about 145,325 (249)

Effects of Implementing an Enhanced Recovery after Surgery pathway on Hysterectomy Postoperative Outcomes [PDF]

Egyptian Journal of Health Care
Background: The implementation of an Enhanced Recovery after Surgery (ERAS) pathway for women undergoing hysterectomy represents a rigorously evidence-based strategy aimed at improving postoperative outcomes, mitigating complications, facilitating ...
Nehal Shalaby Awad Mahmoud, Hanan Abdelrahman Mostafa Kandeel, Samar Elrefaey Elrefaey Abaza   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Revolutionizing perioperative medicine: Technological advancements for enhanced recovery [PDF]

Serbian Journal of Anesthesia and Intensive Therapy
Enhanced Recovery After Surgery (ERAS) is a multimodal, evidence-based approach designed to minimize surgical stress, accelerate recovery, and improve patient outcomes.
Bharadwaj Abhishek
doaj   +1 more source

The benefits of enhanced recovery after surgery

Journal of Visceral Surgery, 2016
Enhanced recovery programs (ERP) after surgery are now being increasingly applied in daily practice. The purpose of this article is to review specific aspects and advantages of this approach. Beyond the reduction in overall morbidity (found for multiple surgical specialties), ERP include issues and stakes that affect patient care, the care team and ...
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

PRF Membranes Enhance Postoperative Recovery After Periapical Surgery: A Single-Blind Randomized Pilot Trial Using 3D Imaging

Oral
Background: Periapical surgery is indicated for persistent periapical lesions that do not respond to conventional endodontic therapy, yet postoperative recovery is often hindered by pain, swelling, and delayed healing.
Martin Major, Melinda Polyák, Tamás Würsching, Gábor Kammerhofer, Éva Kocsis, Zsolt Németh, György Szabó   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

New Advances in Anesthesia Management of Enhanced Recovery After Surgery in Craniotomy

Xiehe Yixue Zazhi, 2021
Enhanced recovery after surgery (ERAS) is a new perioperative management concept with a series of evidence-based clinical optimization protocols to minimize surgical stress response, reduce postoperative complications and enhance patients' recovery ...
LI Yi, LIU Zijia, LABA Ciren, SHEN Le
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Effect of integrated traditional Chinese and western medicine nursing interventions based on enhance recovery after surgery in patients undergoing arthroscopy (基于ERAS理念的膝关节镜手术围手术期中西医结合护理效果观察)

中西医结合护理
Objective To investigate the effect of integrated traditional Chinese and western medicine nursing interventions based on the enhance recovery after surgery in patients undergoing arthroscopy.
ZHANG Wei (张巍)
doaj   +1 more source