Results 101 to 110 of about 5,805,641 (297)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Electrochemical Fabrication of rGO-embedded Ag-TiO2 Nanoring/Nanotube Arrays for Plasmonic Solar Water Splitting

open access: yesNano-Micro Letters, 2019
Effective utilization of hot electrons generated from the decay of surface plasmon resonance in metal nanoparticles is conductive to improve solar water splitting efficiency.
Lixia Sang, Lei Lei, Clemens Burda
doaj   +1 more source

Comparison Of Cfd Simulation To Experiment For Convection Heat Transfer İn An Enhanced Channel

open access: yes, 2006
The numerical and experimental study of heat transfer characteristics in an enhanced channel with turbulent flow is presented. Numerical computations have been done for a periodic element of the channel with periodically fully developed flow using a ...
İslamoğlu, Yaşar   +2 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Dual-Mode Wicking Structures for Enhanced Evaporative Heat Transfer [PDF]

open access: yes, 2012
This paper reports on conceptual design and thermo-fluid characteristics of two-phase flow devices enabled by dualmode wicks. In dual-mode wicking structures, liquid and vapor flow paths are integrated on the same plane and segregated flow of the two ...
TeGrotenhuis, Ward E, Krishnan, Shankar
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Experimental and Numerical Investigation on Non-Newtonian Nanofluids Flowing in Shell Side of Helical Baffled Heat Exchanger Combined with Elliptic Tubes

open access: yesApplied Sciences, 2017
In this paper, an aqueous solution of xanthan gum (XG) at a weight fraction as high as 0.2% was elected as the non-Newtonian base liquid, the multi-walled carbon nanotubes (MWCNTs) dispersed into non-Newtonian XG aqueous at different weight factions of ...
Ziye Ling   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy