Results 41 to 50 of about 201,809 (266)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Theoretical and Experimental Research on Thermal Dynamic Characteristics of Single-Screw Compressor with a New Composite SLIDE Valve

Energies
Based on the single-screw compressor (SSC) structure, a new type of composite slide valve (CSV) has been proposed and designed, featuring internal volume ratios of 2.8, 3.9, and 5.6 and operating under a partial load of 35%.
Shanwei Liu, Ruiping Zhi, Yuting Wu, Yuanwei Lu, Biao Lei, Chongfang Ma   +5 more
doaj   +1 more source

Working Fluid Selection for Organic Rankine Cycle Using Single-Screw Expander

Energies, 2019
The organic Rankine cycle (ORC) is a popular technology used in waste heat recovery and medium-low-temperature heat utilization. Working fluid plays a very important role in ORC.
Xinxin Zhang, Yin Zhang, Min Cao, Jingfu Wang, Yuting Wu, Chongfang Ma   +5 more
doaj   +1 more source

Energy-saving renovation of old urban buildings: A case study of Beijing

Case Studies in Thermal Engineering, 2021
Energy saving and environmental protection have become the core development concept of China construction industry. There are still a large number of old urban buildings in Beijing, whose energy consumption far exceeds the current building energy ...
Xinxin Zhang, Shangyang Nie, Maogang He, Jingfu Wang   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Dynamic Response Characteristics Analysis and Energy, Exergy, and Economic (3E) Evaluation of Dual Loop Organic Rankine Cycle (DORC) for CNG Engine Waste Heat Recovery

Energies, 2021
Frequent fluctuations of CNG engine operating conditions make the waste heat source have uncertain, nonlinear, and strong coupling characteristics. These characteristics are not conducive to the efficient recovery of the DORC system.
Baofeng Yao, Xu Ping, Hongguang Zhang
doaj   +1 more source

HEAT TRANSFER ENHANCEMENT IN PHASE-CHANGE HEAT EXCHANGERS

Aviation, 2014
The paper presents the results of boiling heat transfer enhancement due to the application of additional mesh on the heat exchanger surface. The copper mesh of porosity of 75% was sintered to the copper heater producing strong bonds between the elements.
Chatys, Rafał, Malcho, Milan, Orman, Łukasz J.   +2 more
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source