Results 61 to 70 of about 3,866 (217)

Performance Study on a Single-Screw Expander for a Small-Scale Pressure Recovery System

Energies, 2016
A single-screw expander with 195 mm diameter is developed to recover pressure energy in letdown stations. An experiment system is established using compressed air as a working fluid instead of natural gas.
Guoqiang Li, Yuting Wu, Yeqiang Zhang, Ruiping Zhi, Jingfu Wang, Chongfang Ma   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Preparation and Thermal Model of Tetradecane/Expanded Graphite and A Spiral Wavy Plate Cold Storage Tank

Energies, 2022
A cold storage unit can store the cold energy off-peak and release it for building cooling on-peak, which can reduce the electricity load of air conditioning systems.
Hongguang Zhang, Tanghan Wu, Lei Tang, Ziye Ling, Zhengguo Zhang, Xiaoming Fang   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Review of convective heat transfer enhancement with nanofluids

International Journal of Heat and Mass Transfer, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kakac, Sadik, Pramuanjaroenkij, Anchasa
openaire   +3 more sources

Performance comparison of liquid, vapor, and liquid–vapor injection of single-screw compressor for an air-source heat pump

AIP Advances
Refrigerant injection techniques are usually proposed to improve the performance and reliability of compressors when a single-screw compressor applied to an air-source heat pump works at low temperatures in winter.
Qiangyu Wen, Ruiping Zhi, Yuting Wu, Biao Lei, Yanjun Du   +4 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Performance Analysis and Rapid Optimization of Vehicle ORC Systems Based on Numerical Simulation and Machine Learning

Energies
The organic Rankine cycle (ORC) system is an important technology for recovering energy from the waste heat of internal combustion engines, which is of significant importance for the improvement of fuel utilization. This study analyses the performance of
Xin Wang, Xia Chen, Chengda Xing, Xu Ping, Hongguang Zhang, Fubin Yang   +5 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Electromagnetic enhancement of turbulent heat transfer

Physical Review E, 2008
We performed large eddy simulations (LES) of the turbulent natural convection of an electrically conductive fluid (water with 7% Na2SO4 electrolyte solution) in a moderate (4:4:1) aspect ratio enclosure heated from below and cooled from above and subjected to external nonuniformly distributed electromagnetic fields.
openaire   +4 more sources