Results 41 to 50 of about 199,085 (265)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Theoretical and Experimental Research on Thermal Dynamic Characteristics of Single-Screw Compressor with a New Composite SLIDE Valve

open access: yesEnergies
Based on the single-screw compressor (SSC) structure, a new type of composite slide valve (CSV) has been proposed and designed, featuring internal volume ratios of 2.8, 3.9, and 5.6 and operating under a partial load of 35%.
Shanwei Liu   +5 more
doaj   +1 more source

Working Fluid Selection for Organic Rankine Cycle Using Single-Screw Expander

open access: yesEnergies, 2019
The organic Rankine cycle (ORC) is a popular technology used in waste heat recovery and medium-low-temperature heat utilization. Working fluid plays a very important role in ORC.
Xinxin Zhang   +5 more
doaj   +1 more source

Energy-saving renovation of old urban buildings: A case study of Beijing

open access: yesCase Studies in Thermal Engineering, 2021
Energy saving and environmental protection have become the core development concept of China construction industry. There are still a large number of old urban buildings in Beijing, whose energy consumption far exceeds the current building energy ...
Xinxin Zhang   +3 more
doaj   +1 more source

Heat transfer enhancement by Görtler instability

open access: yesInternational Journal of Heat and Fluid Flow, 2002
Abstract Measurements of mean velocity field and mean temperature field were performed in a concave boundary layer. The growth of the induced Gortler vortices embedded in this boundary layer has been determined in two ways by a criterion based equally on spanwise distortion of velocity or temperature profile.
Toe, R, Ajakh, A, Peerhossaini, H
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Dynamic Response Characteristics Analysis and Energy, Exergy, and Economic (3E) Evaluation of Dual Loop Organic Rankine Cycle (DORC) for CNG Engine Waste Heat Recovery

open access: yesEnergies, 2021
Frequent fluctuations of CNG engine operating conditions make the waste heat source have uncertain, nonlinear, and strong coupling characteristics. These characteristics are not conducive to the efficient recovery of the DORC system.
Baofeng Yao, Xu Ping, Hongguang Zhang
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

HEAT TRANSFER ENHANCEMENT IN PHASE-CHANGE HEAT EXCHANGERS

open access: yesAviation, 2014
The paper presents the results of boiling heat transfer enhancement due to the application of additional mesh on the heat exchanger surface. The copper mesh of porosity of 75% was sintered to the copper heater producing strong bonds between the elements.
Chatys, Rafał   +2 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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