Results 151 to 160 of about 1,780,158 (303)

STING Signaling Drives Production of Innate Cytokines, Generation of CD8⁺ T Cells and Enhanced Protection Against Trypanosoma cruzi Infection. [PDF]

Front Immunol, 2021
Vieira RS, Nascimento MS, Noronha IH, Vasconcelos JRC, Benvenuti LA, Barber GN, Câmara NOS, Kalil J, Cunha-Neto E, Almeida RR.   +9 more
europepmc   +1 more source

Australian quarantine post the Nairn Review [PDF]

The Commonwealth government has accepted the basic tenets of the report of the Australian Quarantine Review (the ‘Nairn Review’), except for the recommendations to establish a statutory authority.
Nunn, Mike J., Tanner, Carolyn
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Enhanced Consumer Healthcare Data Protection Through AI-Driven TinyML and Privacy-Preserving Techniques

IEEE Access
In the recent digital landscape, securing healthcare data stored on personal devices has become imperative due to increasing cyberattacks. Healthcare data inside an organization is often vulnerable to security breaches and requires privacy-preserving ...
S. Aanjankumar, Monoj Kumar Muchahari, Shabana Urooj, Ishmeet Kaur, Rajesh Kumar Dhanaraj, Hanan Abdullah Mengash, S. Poonkuntran, Parag Ravikant Kaveri   +7 more
doaj   +1 more source

Iron oxides in novel skin care formulations attenuate blue light for enhanced protection against skin damage. [PDF]

J Cosmet Dermatol, 2021
Bernstein EF, Sarkas HW, Boland P.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

ENHANCED NUMERICAL BREAKER FAILURE PROTECTION [PDF]

, 2007
In a power system, every apparatus is equipped with a primary protection to detect faults and isolate the equipment by opening a circuit breaker. Circuit breaker failure protection is employed as a means of backup protection to detect failure of a circuit breaker.
openaire  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source