KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Department of Consumer Protection [web site] [Harvested on 2007: Apr. 13]
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Nov. 30, 2010).; At head of title: State of Connecticut.; Harvested from the web on 12/6/10Official website of the Connecticut Department of Consumer Protection ...
core +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Enhanced Surveillance of Clostridioides difficile Infection in Ireland: protocol [v4.2]
Clostridioides difficile infection (CDI) has been a notifiable infectious disease in Ireland since May 2008. Prior to 2012, only new cases of CDI were notifiable. Since January 2012 both new and recurrent cases of CDI are notifiable.
Health Protection Surveillance Centre (HPSC)
core
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Department of Consumer Protection [web site] [Harvested on 2008: Jun. 2]
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Nov. 30, 2010).; At head of title: State of Connecticut.; Harvested from the web on 12/6/10Official website of the Connecticut Department of Consumer Protection ...
core +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Threonine 348 regulates the subcellular localization of PTEN
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Kenya Social Protection Policy 2023 [PDF]
Social Protection is becoming increasingly important worldwide as a powerful tool for combating poverty, inequality, and vulnerability to risks and contingencies across the life cycle, including shocks due to natural disasters, pandemics, and man-induced
Ministry of Labour and Social Protection
core +1 more source
Retraction notice to "Modified Newcastle disease virus vectors expressing the H5 hemagglutinin induce enhanced protection against highly pathogenic H5N1 avian influenza virus in chickens" [Vaccine 32(35) (2014) 4428-4435]. [PDF]
Kim SH +4 more
europepmc +1 more source

