Results 151 to 160 of about 627,492 (310)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
IEEE AccessIn the recent digital landscape, securing healthcare data stored on personal devices has become imperative due to increasing cyberattacks. Healthcare data inside an organization is often vulnerable to security breaches and requires privacy-preserving ...
S. Aanjankumar +7 more
doaj +1 more source
STING Signaling Drives Production of Innate Cytokines, Generation of CD8+ T Cells and Enhanced Protection Against Trypanosoma cruzi Infection. [PDF]
Front Immunol, 2021 Vieira RS +9 more
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
An open platform for rapid-prototyping protection and control schemes with IEC 61850
, 2013 Communications is becoming increasingly important to the operation of protection and control schemes. Although offering many benefits, using standards-based communications, particularly IEC 61850, in the course of the research and development of novel ...
Coffele, Federico +3 more
core +1 more source
Iron oxides in novel skin care formulations attenuate blue light for enhanced protection against skin damage. [PDF]
J Cosmet Dermatol, 2021 Bernstein EF, Sarkas HW, Boland P.
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Long-Term Risks and Short-Term Regulations: Modeling the Transition from Enhanced Oil Recovery to Geologic Carbon Sequestration [PDF]
Recent policy debates suggest that geologic carbon sequestration (GS) likely will play an important role in a carbon-constrained future. As GS evolves from the analogous technologies and practices of enhanced oil recovery (EOR) operations to a long-term,
Vajjhala, Shalini P. +1 more
core
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source