Results 91 to 100 of about 344,740 (342)

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Chronic thoracic hemisection spinal cord injury in adult rats induces a progressive decline in transmission from uninjured fibers to lumbar motoneurons [PDF]

, 2008
Although most spinal cord injuries are anatomically incomplete, only limited functional recovery has been observed in people and rats with partial lesions.
Arko Ghosh, Arsen Hunanyan, Damien D. Pearse, James W. Fawcett, John K. Robinson, Li Lou, Lisa Schnell, Lorne M. Mendell, Martin E. Schwab, Roobeh Golshani, Victor L. Arvanian   +10 more
core   +2 more sources

Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants

Advanced Functional Materials, EarlyView.
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño, Carlos Bendicho‐Lavilla, Haya Alfassam, Bárbara Blanco‐Fernández, Abdul W. Basit, Francisco J. Otero‐Espinar   +5 more
wiley   +1 more source

Reducing gastrointestinal anastomotic leak rates: Review of challenges and solutions [PDF]

, 2016
Various techniques and interventions have been developed in an effort to obviate gastrointestinal anastomotic leaks. This review is intended to delineate potential modifications that can be made to reduce the risk of anastomotic leaks following ...
Philllips, Benjamin
core   +4 more sources

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

Factors associated with pathological complete remission after neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a real-world clinical setting

Frontiers in Oncology
ObjectiveThis study aims to identify factors associated with achieving a pathological complete remission (pCR) in patients with locally advanced rectal cancer (LARC) after neoadjuvant chemoradiotherapy (nCRT).MethodsWe conducted a cohort analysis of 171 ...
Minglin Lin, Minglin Lin, Junsheng Liu, Chongyuan Lan, Ming Qiu, Wei Huang, Wei Huang, Cun Liao, Cun Liao, Sen Zhang, Sen Zhang   +10 more
doaj   +1 more source

Evidence and Practice of Enhanced Lung Recovery after Surgery 
in Patients Undergoing Lung Surgery

Chinese Journal of Lung Cancer, 2017
The clinic application pathway is a variant of the enhanced recovery after surgery (ERAS), which based disease and team. What are the published evidence is conducive to enhanced lung recovery after surgery (ELRAS) in clinical implementation. This article
Guowei CHE
doaj   +1 more source

Biosupercapacitors for Human‐Powered Electronics

Advanced Functional Materials, EarlyView.
Biosupercapacitors are emerging as biocompatible and integrative energy systems for next‐generation bioelectronics, offering rapid charge–discharge performance and mechanical adaptability. This review systematically categorizes their applications from external to organ‐level systems and highlights their multifunctional roles in sensing, actuation, and ...
Suhyeon Kim, Seungho Baek, Woojung Jung, Hayeon Bae, Junyoung Mun, Yong Ho Kim, Sunkook Kim, Jung Ho Kim   +7 more
wiley   +1 more source

Impact of weekday surgery on application of enhanced recovery pathway: a retrospective cohort study. [PDF]

, 2016
To compare the enhanced recovery after surgery (ERAS) protocol compliance and clinical outcomes depending on the weekday of surgery. Cohort of consecutive non-selected patients undergoing elective colorectal surgery from January 2012 to March 2015.
Addor, V., Demartines, N., Grass, F., Hübner, M., Romain, B.   +4 more
core   +1 more source

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

Advanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park, Dong‐yup Lee, Sungsoo Lim, JangHyuk Kim, Min‐Gyu Lee, Chang Seo Park, Hyeonuk Na, Yong Eun Cho, Yun Hyeok Lee, Junsang Doh, Jeong‐Yun Sun   +10 more
wiley   +1 more source