Results 281 to 290 of about 1,693,537 (318)
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Immunogenetics, 1996
Hypermutation at the immunoglobulin (Ig) loci increases the mutation rate more than 10(5)-fold over the normal, spontaneous rate. We studied two kinds of cis-acting elements - 3' enhancers and promoters - in a system in which a gene encoding the mu heavy (H) chain (Igm) is transfected in vitro into a cell line with an active Ig mutator.
J, Bachl, M, Wabl
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Hypermutation at the immunoglobulin (Ig) loci increases the mutation rate more than 10(5)-fold over the normal, spontaneous rate. We studied two kinds of cis-acting elements - 3' enhancers and promoters - in a system in which a gene encoding the mu heavy (H) chain (Igm) is transfected in vitro into a cell line with an active Ig mutator.
J, Bachl, M, Wabl
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Enhancer Transcription And Enhancer Function
The FASEB Journal, 2016We utilize a combination of genome‐wide and genetic approaches to investigate molecular mechanisms that underlie the development and function of macrophages. Our studies suggest a relatively simple model of hierarchical interactions between lineage‐determining and signal‐dependent transcription factors that are required to select functional cis‐active ...
Christopher Glass +6 more
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Enhancing Learning by Enhancing Teaching
2015This chapter provides an overview of the enhancement of teaching and learning in a higher education setting, facilitated by two enhancement initiatives. The PRO-Teaching project and the PACES are complementary cross-disciplinary teamimplemented initiatives aimed at enhancing the quality of teaching and curriculum design.
Klopper, Christopher +2 more
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Science, 1972
Presentation of a masking stimulus enhances, rather than detracts from, detectability of certain multisegment targets. Present theories of backward masking cannot account for this "backward enhancement" effect, which resembles another puzzling phenomenon, previously reported as target recovery or disinhibition.
W N, Dember, M, Stefl
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Presentation of a masking stimulus enhances, rather than detracts from, detectability of certain multisegment targets. Present theories of backward masking cannot account for this "backward enhancement" effect, which resembles another puzzling phenomenon, previously reported as target recovery or disinhibition.
W N, Dember, M, Stefl
openaire +2 more sources
Nature Reviews Genetics, 2019
A study in Cell identifies a mechanism by which exon splicing can increase gene expression through the activation of weak upstream promoters.
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A study in Cell identifies a mechanism by which exon splicing can increase gene expression through the activation of weak upstream promoters.
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ENHANCED CREATIVITY, ENHANCED WRITING, ENHANCED LEARNING!
2012If a story is a story with its characters living and/or dying in it, then the main concern of short story writers is to create and enliven them. This paper aims to show an alternative way of initiating creative writing in a literature class by encouraging students to move the characters created in different genres such as poetry, painting and fiction ...
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Journal of Medical Ethics, 2016
Moral enhancement can be an attractive proposal, but contrary to cognitive enhancement, it is hard to define what kind of intervention would constitute moral enhancement. In an ongoing debate about the subject, Douglas argued that biomedically decreasing countermoral emotions would do so and would be morally permissible in particular cases.
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Moral enhancement can be an attractive proposal, but contrary to cognitive enhancement, it is hard to define what kind of intervention would constitute moral enhancement. In an ongoing debate about the subject, Douglas argued that biomedically decreasing countermoral emotions would do so and would be morally permissible in particular cases.
openaire +2 more sources

