Results 51 to 60 of about 1,091,280 (248)

Typical Enhancers, Super-Enhancers, and Cancers

Cancers, 2022
Non-coding segments of the human genome are enriched in cis-regulatory modules that constitute functional elements, such as transcriptional enhancers and Super-enhancers. A hallmark of cancer pathogenesis is the dramatic dysregulation of the “archetype” gene expression profiles of normal human cells.
Marianna A. Koutsi, Marialena Pouliou, Lydia Champezou, Giannis Vatsellas, Angeliki-Ioanna Giannopoulou, Christina Piperi, Marios Agelopoulos   +6 more
openaire   +3 more sources

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Dismissed Mines: From the Past to the Future

Heritage, 2023
Today, dismissed mines are considered significant local tangible and intangible cultural heritage elements and they are more and more often at the core of dedicated enhancement processes, being sometimes inscribed in the UNESCO list; included in geoparks;
Roberta Varriale, Barbara Aldighieri, Laura Genovese   +2 more
doaj   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Research Progress in the Application of Ultrasonic Technology in the Regeneration of Desiccants for Air-conditioning

Zhileng xuebao, 2012
This paper has had a review of the research progress in the regeneration of dessicants (solid and liquid) assisted by the ultrasonic technology. Particularly, the effect of ultrasonic on the enhancement of desiccant regeneration, the energy consumption ...
Yao Ye
doaj  

NeuroRight to Equal Access to Mental Augmentation

Revista Iberoamericana de Bioética, 2021
This paper addresses the different discussions that led to the creation of the NeuroRights Initiative and the proposal for a NeuroRight to equal access to mental augmentation.
Diego Alejandro Borbón Rodríguez, Luisa Fernanda Borbón Rodríguez, María Alejandra León Bustamante   +2 more
doaj   +1 more source

Autonomy‐Enhancing Paternalism [PDF]

Kyklos, 2014
SummaryWe present a form of soft paternalism called “autonomy‐enhancing paternalism” that seeks to increase individual well‐being by facilitating the individual ability to make critically reflected, autonomous decisions. The focus of autonomy‐enhancing paternalism is on helping individuals to become better decision‐makers, rather than on helping them ...
Binder, Martin, Lades, Leonhard
openaire   +5 more sources

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Background Parenchymal Enhancement and Fibroglandular Tissue Proportion on Breast MRI: Correlation with Hormone Receptor Expression and Molecular Subtypes of Breast Cancer

European Journal of Breast Health, 2017
Objective:To assess the relationship between background parenchymal enhancement (BPE) and fibroglandular tissue (FGT) proportion on breast magnetic resonance imaging (MRI) and hormone receptor expression and molecular subtypes in invasive breast cancer ...
Mesut Öztürk, Ahmet Veysel Polat, Yurdanur Süllü, Leman Tomak, Ayfer Kamalı Polat   +4 more
doaj   +1 more source