Results 211 to 220 of about 109,726 (240)

Amino-terminal extension analogs of methionine-enkephalin

Biochemical and Biophysical Research Communications, 1978
Abstract Five NH 2 -terminal extension analogs of methionine-enkephalin have been synthesized by solid phase methodology and their morphinomimetic activity determined in the guinea pig ileum-myenteric plexus preparation. Relative to methionine-enkephalin which corresponds to β-LPH-(61–65) and arbitrarily assigned a potency value of 100, β-LPH-(60–65),
Roger Guillemin, Scott Minick, Nicholas Ling   +2 more
openaire   +3 more sources

Methionine Enkephalin, But not Leucine Enkephalin, is Excreted in Bile [PDF]

Clinical Science, 1988
M S Losowsky, Judith Thornton
openaire   +1 more source

Determination of Methionine-Enkephalin and Leucine-Enkephalin in Human Cerebrospinal Fluid

1983
Abstract Commercially available radio immunoassay kits were used to find out the concentrations of met-enkephalin and leu-enkephalin in the human concentrated CSF samples in the presence of seven proteinase inhibitors. Reference values were established for lumbar CSF. No correlation was found between total protein content and both enkephalins in CSF.
A. Singh, B. Merten, T.O. Kleine
openaire   +2 more sources

Methionine Enkephalin: A New Cytokine—Human Studies

Clinical Immunology and Immunopathology, 1997
The effects of methionine enkephalin (met-enkephalin) on human immune function are reviewed. This pentapeptide functions to upregulate, or enhance, immune function in the majority of donor samples at low doses and suppresses at high doses. The influence of this molecule is shared by the central nervous, neuroendocrine, and immune systems.
Ronald B. Herberman, Nicholas P. Plotnikoff, Robert E. Faith, Anthony J. Murgo, Robert A. Good   +4 more
openaire   +3 more sources

Augmenting effect of methionine-enkephalin on interleukin-6 production by cytokine-stimulated murine macrophages

Neuropeptides, 2000
The effects of methionine-enkephalin on the production of interleukin-6 by activated peritoneal murine macrophages were studied. Macrophage were activated with interleukin-1beta or interferon-gamma in the presence or absence of graded concentrations of ...
J. Kowalski, K. Makowiecka, D. Belowski, Z. Herman   +3 more
semanticscholar   +1 more source

Immunocytochemical localization of methionine enkephalin: Preliminary observations

Life Sciences, 1977
Abstract Antiserum directed against methionine enkephalin (metenkephalin) was used to determine its anatomical distribution in rat brain. Cross reactivity of that antiserum was not detectable against leucine enkephalin (leu-enkephalin), β-lipotropin (β-LPH), β-endorphin or assorted peptide fragments of met-enkephalin; alpha-endorphin was 370 times ...
Sue Sullivan, Huda Akil, Jack D. Barchas, Stanley J. Watson   +3 more
openaire   +3 more sources

Methionine-enkephalin and morphine: Amount ejected microiontophoretically

Journal of Neuroscience Methods, 1981
The microiontophoretic transport numbers of Met-enkephalin and morphine were determined by ejecting the tritiated compounds from both 5-barrel and 7-barrel micro-pipettes into a small volume of 0.9% NaCl, using a series of ejection currents and various timed durations.
Henry J. Haigler, R. Scott Turner, David A. Hosford   +2 more
openaire   +3 more sources

A further characterization of the differential effects of leucine enkephalin, methionine enkephalin and their analogs on morphine-induced analgesia.

Journal of Pharmacology and Experimental Therapeutics, 1979
J. L. Vaught, A. Takemori
semanticscholar   +1 more source

Plasma methionine-enkephalin in PTSD

Biological Psychiatry, 1991
Aron D. Mosnaim, Javier Puente, Marion E. Wolf, Romeo C. Ignacio   +3 more
openaire   +3 more sources

The glutamate decarboxylase-, leucine enkephalin-, methionine enkephalin-and substance P-immunoreactive neurons in the neostriatum of the rat and cat: Evidence for partial population overlap

Neuroscience, 1986
G. Penny, S. Afsharpour, S. Kitai
semanticscholar   +1 more source