FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Inflammatory Presentation of Orbital Metastasis Years after Bilateral Mastectomy for Breast Cancer: A Case Report and Literature Review. [PDF]
Case Rep OphthalmolAhdoot R +3 more
europepmc +1 more source
Application of deep learning based on convolutional neural network model in multimodal ultrasound diagnosis of unexplained cervical lymph node enlargement [PDF]
Shanshan Jiang +4 more
openalex +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
ADRENAL HISTOPLASMOSIS AND BILATERAL ADRENAL ENLARGEMENT
, 2019 Waye Hann K, Norasyikin Aw, Nor Azmi K
openalex +2 more sources
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
FEBS Open Bio, EarlyView.Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
Immunohistochemical Analysis of Tom20 in Choroid Plexus Epithelial Cells From Elderly Brains With Neurodegenerative Diseases. [PDF]
NeuropathologyMurakami R +8 more
europepmc +1 more source
Risk factors for incident atrial fibrillation with and without left atrial enlargement in women
, 2013 David Conen +4 more
openalex +2 more sources