Results 61 to 70 of about 65,679 (312)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Weak Measurements with Entangled Probes
Encoding the imaginary part of a weak value onto an initially entangled probe can modify its entanglement content - provided the probe observable can distinguish between states of different entropies.
Korolkova, Natalia, Menzies, David
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
We investigated nano-structural changes of cellulose dissolved in 1-ethyl-3-methylimidazolium acetate—an ionic liquid (IL)—using a small angle X-ray scattering (SAXS) technique over the entire concentration range (0–100 mol %).
Takatsugu Endo +4 more
doaj +1 more source
Shear flow effects on phase separation of entangled polymer blends [PDF]
We introduce an entanglement model mixing rule for stress relaxation in a polymer blend to a modified Cahn-Hilliard equation of motion for concentration fluctuations in the presence of shear flow.
A. Onuki +18 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Generalized concentratable entanglement via parallelized permutation tests
Multipartite entanglement is an essential resource for quantum information theory and technologies, but its quantification has been a persistent challenge.
Xiaoyu Liu +3 more
doaj +1 more source
Design and application of functional soft materials based on highly-entangled networks
Highly entangled networks,as a novel design strategy for soft materials,effectively address the contradiction among strength,toughness,and fatigue resistance in traditional crosslinked materials by regulating the topological entanglement structure of ...
GAO Lu, WU Wenjuan, ZHAO Chuanzhuang
doaj +1 more source

