Results 1 to 10 of about 58,396 (231)

Ivacaftor pharmacokinetics and lymphatic transport after enteral administration in rats [PDF]

Frontiers in Pharmacology
Background: Ivacaftor is a modern drug used in the treatment of cystic fibrosis. It is highly lipophilic and exhibits a strong positive food effect. These characteristics can be potentially connected to a pronounced lymphatic transport after oral administration.Methods: A series of studies was conducted to describe the basic pharmacokinetic parameters ...
Jiří Pozniak, Pavel Ryšánek, David Smrčka, Petr Kozlík, Tomáš Křížek, Jaroslava Šmardová, Anežka Nováková, Debanjan Das, Daniel Bobek, Mahak Arora, Jiří Hofmann, Tereza Doušová, Martin Šíma, Ondřej Slanař   +13 more
europepmc   +6 more sources

Small intestinal development in suckling rats after enteral obestatin administration. [PDF]

PLoS ONE, 2018
This study investigated the effect of enteral administration of obestatin on the development of small intestine, as well as oxidative stress markers and trancriptomic profile of gastrointestinal genes. Suckling rats were assigned to 3 groups treated with:
Monika Słupecka-Ziemilska, Paulina Grzesiak, Michał Jank, Alicja Majewska, Agnieszka Rak, Paweł Kowalczyk, Ikuo Kato, Atsukazu Kuwahara, Jarosław Woliński   +8 more
doaj   +4 more sources

Transition phase of nutrition—optimizing nutrient administration [PDF]

Frontiers in Pediatrics
This discussion explores the complex aspects of managing nutrition for preterm infants during the critical transition from exclusive parenteral nutrition (PN) to full enteral feeding (EN). The primary objectives of nutritional care in this very low birth
Pradeep Alur, Sumana Ramarao
doaj   +2 more sources

Low-methoxy pectin-containing enteral nutrition in critical care for intestinal tolerance (LOME-PECT): Study protocol for a randomized controlled trial. [PDF]

PLoS ONE
BackgroundEnteral nutrition is preferable over parenteral nutrition for critically ill patients, but is often discontinued due to enteral feeding intolerance.
Shizuka Kashiwagi, Shunsuke Takaki, Yasufumi Oi, Hiroshi Honzawa, Ryo Yamamoto, Ikutaro Yamashita, Izumi Ohki, Shigeki Fujitani, Akiyoshi Nagatomi, Yuki Ohshima, Minoru Yoshida, Hideki Yoshida, Miyuki Kurisu, Yuji Takahashi, Hideki Hashimoto, Yasuaki Koyama, Junji Hatakeyama, Satoru Shinoda, Nobuyuki Yokoyama, Kensuke Nakamura   +19 more
doaj   +2 more sources

Intravenous dexamethasone administration during anesthesia induction can improve postoperative nutritional tolerance of patients following elective gastrointestinal surgery: A post-hoc analysis

Frontiers in Nutrition, 2023
AimTo investigate the effect of intravenous dexamethasone administration on postoperative enteral nutrition tolerance in patients following gastrointestinal surgery.MethodsBased on the previous results of a randomized controlled study to explore whether ...
Feng Tian, Feng Tian, Xinxiu Zhou, Junke Wang, Mingfei Wang, Zhou Shang, Leping Li, Leping Li, Changqing Jing, Changqing Jing, Yuezhi Chen, Yuezhi Chen   +11 more
doaj   +1 more source

Effect of enterally administered sleep-promoting medication on the intravenous sedative dose and its safety and cost profile in mechanically ventilated patients: A retrospective cohort study.

PLoS ONE, 2021
BackgroundThe clinical effect of enteral administration of sleep-promoting medication (SPM) in mechanically ventilated patients remains unclear. This study aimed to investigate the relationship between enteral SPM administration and the intravenous ...
Takefumi Tsunemitsu, Yuki Kataoka, Masaru Matsumoto, Takashi Hashimoto, Takao Suzuki   +4 more
doaj   +1 more source

ENTERAL ADMINISTRATION OF INSULIN IN THE RAT [PDF]

British Journal of Pharmacology, 1981
The effect of the surfactant, Cetomacrogol 1000, on the absorption of insulin across the rectal mucosa has been studied. Rectal administration of microenemata containing Cetomacrogal 1000 and insulin causes a rise in the plasma concentration of insulin and a consequent fall in the blood glucose concentration in diabetic and non‐diabetic rats.
Ehud Ziv, D. Lichtenberg, Elliot M. Berry, Amiram Eldor, Miriam Kidron, Hanoch Bar-On   +5 more
openaire   +3 more sources

Management Considerations for Pulmonary Arterial Hypertension Pharmacotherapy in the Intensive Care Unit

Pharmacy, 2023
Pulmonary arterial hypertension is a rare and progressive disease with significant morbidity and mortality risk. Several medications targeting three major disease pathways are approved for treatment.
Elizabeth M. Foster, Danine Sullinger, James C. Coons   +2 more
doaj   +1 more source

The use of Lactobacillus plantarum 299v (DSM 9843) in cancer patients receiving home enteral nutrition – study protocol for a randomized, double-blind, and placebo-controlled trial

Nutrition Journal, 2020
Background Nutritional treatment is one of the most important components of multidisciplinary anti-cancer therapy. Home enteral nutrition is considered as a safe procedure, however, it may be associated with the risk of side effects, such as nausea ...
Karolina Kaźmierczak-Siedlecka, Marcin Folwarski, Karolina Skonieczna-Żydecka, Jakub Ruszkowski, Wojciech Makarewicz   +4 more
doaj   +1 more source

Preparing and administering medications via enteral feeding tubes: a guideline for clinical pharmacists and multi-professional team

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2021
Objective: To identify the most prescribed drugs by enteral feeding tube in a public hospital and to a guideline for safe medication preparation and administration via enteral feeding tubes.
Danyara BATISTA, Paula M. OLIVEIRA-LEMOS   +1 more
doaj   +1 more source