The administration of antiretroviral therapy (ART) in intubated critically ill patients may be challenging. Limited pharmacokinetic data exist characterizing the effects of crushed ART with subsequent enteral administration on antiretroviral drug ...
Sarah Lynn Turley PharmD, BCPS +1 more
doaj +2 more sources
Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction. [PDF]
Significance Since sepsis induces a sustained immunosuppression responsible for secondary infections acquisition and late mortality, restoring immune function would result in a better outcome.
Reizine F +28 more
europepmc +2 more sources
ENTERAL ADMINISTRATION OF INSULIN IN THE RAT [PDF]
The effect of the surfactant, Cetomacrogol 1000, on the absorption of insulin across the rectal mucosa has been studied. Rectal administration of microenemata containing Cetomacrogal 1000 and insulin causes a rise in the plasma concentration of insulin and a consequent fall in the blood glucose concentration in diabetic and non‐diabetic rats.
H, Bar-On +5 more
openaire +3 more sources
In Vivo Study of Entero- and Hepatotoxicity of Silver Nanoparticles Stabilized with Benzyldimethyl-[3-myristoylamine)-propyl]ammonium Chloride (Miramistin) to CBF1 Mice upon Enteral Administration. [PDF]
Silver nanoparticles (AgNPs) are the most widely studied antimicrobial nanomaterials. However, their use in biomedicine is currently limited due to the availability of data that prove the nanosilver toxicity associated primarily with oxidative stress ...
Krutyakov YA +7 more
europepmc +2 more sources
Early Enteral Administration of a Complex Lipid Emulsion Supplement Prevents Postnatal Deficits in Docosahexaenoic and Arachidonic Acids and Increases Tissue Accretion of Lipophilic Nutrients in Preterm Piglets. [PDF]
BACKGROUND Preterm delivery and current nutrition strategies result in deficiencies of critical long-chain fatty acids (FAs) and lipophilic nutrients, increasing the risk of preterm morbidities. We sought to determine the efficacy of preventing postnatal
Akinsulire O +20 more
europepmc +2 more sources
Drug administration via enteral feeding tubes in residential care facilities for individuals with intellectual disability: an observational study [PDF]
Elke Joos +5 more
openalex +2 more sources
Alpha-tocopherol in intravenous lipid emulsions imparts hepatic protection in a murine model of hepatosteatosis induced by the enteral administration of a parenteral nutrition solution. [PDF]
Intestinal failure-associated liver disease (IFALD) is a risk of parenteral nutrition (PN)-dependence. Intravenous soybean oil-based parenteral fat can exacerbate the risk of IFALD while intravenous fish oil can minimize its progression, yet the ...
Fell GL +10 more
europepmc +2 more sources
Enteral administration of protein supplement and valproate: A potential pharmacokinetic interaction. [PDF]
Background Valproic acid (VPA) and its derivatives are highly protein bound. Certain highly protein bound medications (eg, phenytoin) have specific administration instructions for patients on enteral nutrition supplements to optimize absorption of the ...
VandenBerg A, Broadway J.
europepmc +2 more sources
Bile pigment pharmacokinetics and absorption in the rat: therapeutic potential for enteral administration [PDF]
Andrew C. Bulmer +5 more
openalex +2 more sources
Dysphagia is increasingly common in older adults; it is especially prevalent in long-term care settings. Patients with dysphagia likely require pharmacologic treatment for multiple comorbidities but may find it difficult or impossible to swallow oral ...
Amie Blaszczyk +5 more
semanticscholar +1 more source

