Results 11 to 20 of about 8,316 (301)

Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation

open access: yesPharmaceutics, 2023
Oral delivery of peptides and biological molecules promises significant benefits to patients as an alternative to daily injections, but the development of these formulations is challenging due to their low bioavailability and high pharmacokinetic ...
Puneet Tyagi   +12 more
doaj   +1 more source

Development of Enteric-coated Tablets of Sodium 4,4'-(propnadiamido)dibenzoate

open access: yesРазработка и регистрация лекарственных средств, 2022
Introduction. Enteric coat have a wide range of functions: from protecting the API from the adverse effects of the acidic environment of the stomach to targeted delivery to certain parts of the intestine in order to increase the effectiveness of the drug.
Ju. M. Kotsur   +2 more
doaj   +1 more source

3D Printing for a novel Enteric Coated Ibuprofen Tablets

open access: yesBritish Journal of Pharmacy, 2023
3D printing has the potential to play a significant role in pharmaceutical research by optimizing medication usage and minimizing adverse effects through the creation of personalised dosage forms. However, various obstacles hinder the full utilisation of
Ahmed Nassar   +2 more
doaj   +1 more source

Development of Duloxetine Hydrochloride Tablets for Delayed and Complete Release Using Eudragit L 100

open access: yesInternational Journal of Polymer Science, 2021
The purpose of the research was to optimize the preparation of duloxetine hydrochloride (duloxetine HCl) delayed release tablets. Duloxetine HCl produces a toxic substance called alpha-naphthol when duloxetine HCl is in contact with gastric fluid.
M. Yasmin Begum   +6 more
doaj   +1 more source

A brief review on recent advancement of tablet coating technology

open access: yesJournal of Applied Pharmaceutical Research, 2022
A tablet can be defined as a solid unit dosage form. There are several reasons for coating of solid dosage form, the most important reason is to control the release profile & also to control the bioavailability parameters of the APIs (Active ...
Debgopal Ganguly   +6 more
doaj   +1 more source

Characterization of enteric-coated erythromycin tablets by Raman mapping and its pharmaceutical evaluation

open access: yesFrontiers in Chemistry, 2023
Enteric tablet coating thickness is a critical quality attribute of the coating process that can affect dissolution behavior in vitro as well as release in vivo.
Wenbo Zou   +3 more
doaj   +1 more source

Safety, tolerability, pharmacokinetic/pharmacodynamic characteristics of bersiporocin, a novel prolyl‐tRNA synthetase inhibitor, in healthy subjects

open access: yesClinical and Translational Science, 2023
Bersiporocin, a novel first‐in‐class prolyl‐tRNA synthetase (PRS) inhibitor currently under clinical development, was shown to exert an antifibrotic effect through the downregulation of collagen synthesis in various pulmonary fibrosis models.
Min Young Park   +8 more
doaj   +1 more source

Quality by Design Applied Development of Immediate-Release Rabeprazole Sodium Dry-Coated Tablet

open access: yesPharmaceutics, 2021
The aim of this study was to develop immediate-release oral rabeprazole sodium tablets with rapid efficacy and gastric stability for the treatment of gastroesophageal reflux disease.
Sang-Ho Lee, Joo-Eun Kim
doaj   +1 more source

Enteric-Coated Cologrit Tablet Exhibit Robust Anti-Inflammatory Response in Ulcerative Colitis-like In-Vitro Models by Attuning NFκB-Centric Signaling Axis

open access: yesPharmaceuticals, 2022
Ulcerative colitis (UC) is an inflammatory bowel disease that affects the patients’ colorectal area culminating in an inflamed ‘leaky gut.’ The majority of UC treatments only provide temporary respite leading to its relapse.
Acharya Balkrishna   +6 more
doaj   +1 more source

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