Results 261 to 270 of about 8,316 (301)

A Walk in the Park: Influence of Natural Co‐Exposure to Grass Pollen and Fungal Spores on Nasal Mycobiome and Cytokine Responses

Clinical &Experimental Allergy, EarlyView.
Volunteers stayed 3 h indoors and followed 1 h outdoors in a flowering meadow. Nasal mycobiome was analysed and aeroallergen content measured in nasal filters. Airborne fungal spores were quantified and fungal isolates were sequenced. Isolated fungal spores were used for stimulation of nasal epithelial cells.
Annika Eggestein, Denise Rauer, Selina M. Herrmann, Franziska Kolek, Vivien Leier‐Wirtz, Swetlana Urban, Bärbel Foesel, Michael Schloter, Madhumita Bhattacharyya, Ioana Pyrri, Matthias Reiger, Vera Schwierzeck, Claudia Hülpüsch, Claudia Traidl‐Hoffmann, Athanasios Damialis, Stefanie Gilles   +15 more
wiley   +1 more source

Massive Valproic Acid Overdose With Confirmed Pharmacobezoar Formation and Neuromuscular Toxicity: A Case Report and Literature Review. [PDF]

Cureus
Alrazooqi MK, Abumuaileq L, Zia S, Kazim S.   +3 more
europepmc   +1 more source

Pediatric Investigation Plans for seizure and epilepsy treatments: An analysis since the implementation of the European Pediatric Regulation in 2006

Epilepsia, EarlyView.
Abstract Objective A Pediatric Investigation Plan (PIP) implemented under the European Pediatric Regulation (EC No. 1901/2006) aims to ensure early and systematic evaluation of medicines for children. We analyze PIPs for antiseizure medications (ASMs) submitted to the European Medicines Agency (EMA) since 2006, characterizing their content, focusing on
Valeria Agostini, Stéphane Auvin
wiley   +1 more source

An ADR pharmaceutical care for severe gastrointestinal bleeding of rivaroxaban in a patient with nonvalvular atrial fibrillation based on TDM and genetic testing: a case report. [PDF]

BMC Med Genomics
Huang Y, Gao H, Chen M, Lin Y, Liu H, Chen M.   +5 more
europepmc   +1 more source

Equine botulism

Equine Veterinary Journal, EarlyView.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik, Robert Whitlock, Amy Johnson   +2 more
wiley   +1 more source

Solidification of SNEDDS Using Mesoporous Carriers (2020-2025): A Review of Design, Biopharmaceutical Enhancement, and Therapeutic Impact. [PDF]

Drug Des Devel Ther
Priani SE, Nurhaliza A, Chaerunisaa AY, Wilar G, Sopyan I.   +4 more
europepmc   +1 more source

Efficacy and welfare effects of different forms of physical restraint for upper airway endoscopy of horses

Equine Veterinary Journal, EarlyView.
Abstract Background Physical restraint of horses for veterinary procedures is necessary to allow completion of tasks effectively and without injury to patient or personnel. Objectives To compare physiological effects and behavioural responses to four commonly used restraint techniques for upper respiratory tract (URT) endoscopy in unsedated horses ...
Claire O'Brien, Olivier Simon, Samantha H. Franklin, Gustavo Ferlini Agne, Sarah Weaver, Sharanne L. Raidal   +5 more
wiley   +1 more source

Relationship between fetal-type posterior cerebral artery and basilar artery atherosclerosis. [PDF]

Front Neurol
Zheng L, Chen Y, Lin X, Deng S, Sun B, Zheng J, Zeng F, Xue Y.   +7 more
europepmc   +1 more source

Development and biopharmaceutical evaluation of press-coated tablets taking account of circadian rhythms of disease [PDF]

, 2001
Halsas, Marikki
core  

Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells

The FEBS Journal, EarlyView.
Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari, Kathryn Volkening, Zahra Nayeri, Aysegul Yucel Polat, Neil Donison, Jacqueline Palik, Michael J. Strong   +6 more
wiley   +1 more source