Results 21 to 30 of about 8,316 (301)

Oral Delivery of Niclosamide as an Amorphous Solid Dispersion That Generates Amorphous Nanoparticles during Dissolution

Pharmaceutics, 2022
Niclosamide is an FDA-approved anthelmintic that is being studied in clinical trials as a chemotherapeutic and broad-spectrum antiviral. Additionally, several other applications are currently in the preclinical stage.
Miguel O. Jara, Zachary N. Warnken, Sawittree Sahakijpijarn, Rishi Thakkar, Vineet R. Kulkarni, Dale J. Christensen, John J. Koleng, Robert O. Williams   +7 more
doaj   +1 more source

In Vitro Evaluation of Eslicarbazepine Delivery via Enteral Feeding Tubes [PDF]

, 2017
Purpose: The feasibility of preparing an eslicarbazepine acetate suspension using Aptiom tablets for administration via enteral feeding tubes was evaluated.
Dave, Vivek S, Hughes, Susan, Reindel, Kristin, Zhao, Fang   +3 more
core   +2 more sources

Formulation and development of Serratiopeptidase enteric coated tablets and analytical method validation by UV Spectroscopy

International Journal of Analytical Chemistry, 2021
Serratiopeptidase (SRP) is a proteolytic enzyme that emerged as one of the most potent anti-inflammatory and analgesic drugs. The purpose of the present study was to formulate and evaluate enteric-coated tablets for SRP and investigate their stability ...
Vijay Kumar Panthi, Saurav Kumar Jha, Raghvendra Chaubey, Rudra Pangeni   +3 more
doaj   +1 more source

In vitro dissolution of proton-pump inhibitor products intended for paediatric and geriatric use in physiological bicarbonate buffer [PDF]

, 2015
Peer reviewedFinal Accepted ...
Liu, Fang, Shokrollahi, Honaz
core   +1 more source

In Vivo Evaluation of a Gastroretentive Drug Delivery System Based on Enteric-Coated Floating Tablets [PDF]

, 2015
Floating dosage forms are supposed to exhibit an enhanced gastric residence time. Their development is challenging as the prediction of the retention potential in humans based on in vitro studies and animal models is difficult.
Alles, Rainer, Donzelli, Massimiliano, Eberle, Veronika A., Huwyler, Jörg, Puchkov, Maxim   +4 more
core   +1 more source

Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions

Frontiers in Pharmacology, 2023
Objective: The main purpose of this study was to evaluate the pharmacokinetics, bioequivalence, and safety properties between a new generic and a brand reference formulation of esomeprazole enteric-coated tablets 20 mg in healthy Chinese subjects under ...
Ying Ding, Nannan Chu, Linling Que, Kai Huang, Yuanxing Chen, Wei Qin, Zhenzhong Qian, Yunfei Shi, Zhen Xu, Qing He   +9 more
doaj   +1 more source

Hot-melt sub- and outercoating combined with enteric aqueous coating to improve the stability of aspirin tablets

Asian Journal of Pharmaceutical Sciences, 2017
Aspirin is apt to hydrolyze. In order to improve its stability, a new method has been developed involving the application of hot-melt sub- and outercoating combined with enteric aqueous coating.
Xiuzhi Wang, Puxiu Wang, Chenglong Huang, Xiaoyang Lin, Haoyu Gong, Haibing He, Cuifang Cai   +6 more
doaj   +1 more source

Evolution of a physiological pH 6.8 bicarbonate buffer system: application to the dissolution testing of enteric coated products. [PDF]

, 2011
The use of compendial pH 6.8 phosphate buffer to assess dissolution of enteric coated products gives rise to poor in vitro-in vivo correlations because of the inadequacy of the buffer to resemble small intestinal fluids.
Abdul W. Basit, Agyilirah, Banwell, Bianchini, Bogentoft, Boni, Bruce, Chan, Cole, Dangel, Davis, Dressman, Ebel, Eckersley, Evans, Fadda, Fadda, Fadda, Fallingborg, Fang Liu, Garcia-Arieta, Hamid A. Merchant, Hardy, Harianawala, Ibekwe, Kararli, Lehmann, Lindahl, Liu, Maram Alkademi, McConnell, McNamara, Narasimhan, Nesbitt, Nguyen, Ozturk, Phillips, Rucha P. Kulkarni, Schiller, Shek, Sheng, Spitael, Spitael, Vanderhoff, Wilding   +44 more
core   +1 more source

Water dispersible microbicidal cellulose acetate phthalate film [PDF]

, 2003
BACKGROUND: Cellulose acetate phthalate (CAP) has been used for several decades in the pharmaceutical industry for enteric film coating of oral tablets and capsules.
A Robert Neurath, A Stone, AC Gerbase, AJ Nahmias, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AV Kabanov, B Kovacs, C Coggins, CV Uglea, D Quintanar-Guerrero, DL Jones, DS Jones, G Green, G Ramjee, GN Milligan, H Arwidsson, H Chakraborty, H Ibrahim, H.L.,Jr. Martin, IJ Rosenstein, J Liao, JA Rottingen, JM Mann, JR Dyer, K Stiasny, KA Gates, KH Manson, KR Tambweker, L Van Damme, M Over, M Ratterree, MK Stafford, Nathan Strick, P Sakellariou, PL Perine, R Duncan, R Rustomjee, RE Roddy, RJ Harwood, RN Fichorova, RN Fichorova, SD Holmberg, SJ Reynolds, SR Goskonda, T Gyotoku, T Kawamura, T Kietzke, T Vemba, V Baeyens, V Rosilio, Yun-Yao Li   +57 more
core   +2 more sources

Comparative Bioavailability Study of Two 81 mg Coated Tablet Formulations of Acetylsalicylic Acid in Fasting Healthy Volunteers [PDF]

, 2017
Introduction: Low-dose acetylsalicylic acid is used as antithrombotic agent and the enteric-coated formulations are widely used to minimize the gastrointestinal side effects. Aim: To compare the bioavailability of two acetylsalicylic acid formulations
Antunes, Nj, De Nucci, G., DI VAIO, Paola, Dolores, Rc, Magli, Elisa, Moreno, R   +5 more
core   +1 more source