Optimal protection of stabilised dry live bacteria from bile toxicity in oral dosage forms by bile acid adsorbent resins [PDF]
, 2010 We previously found that dried live bacteria of a vaccine strain can be temporarily sensitive to bile acids and suggested that Bile Adsorbing Resins (BAR) can be used in oral vaccine tablets to protect dried bacteria from intestinal bile. Here, we report
Chatterjee, Pratichi +4 more
core +1 more source
Targeted colonic release formulations of mesalazine - A clinical pharmaco-scintigraphic proof-of-concept study in healthy subjects and patients with mildly active ulcerative colitis. [PDF]
, 2022 Colonic targeting of orally applied therapeutic drugs remains a challenge. Tablet coatings relying on gastrointestinal pH and colonic bacterial enzymes as triggers in association with an inner alkaline layer are expected to improve targeting efficiency ...
Bravo, R +8 more
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Canadian Journal of Gastroenterology, 1997 This study compared the 24 h intragastric pH profile and bioavailability at repeated dosing conditions of the omeprazole 20 mg enteric-coated tablet versus the 20
ABR Thomson +5 more
doaj +1 more source
In Vitro Evaluation of Eslicarbazepine Delivery via Enteral Feeding Tubes [PDF]
, 2017 Purpose: The feasibility of preparing an eslicarbazepine acetate suspension using Aptiom tablets for administration via enteral feeding tubes was evaluated.
Dave, Vivek S +3 more
core +2 more sources
Canadian Journal of Gastroenterology, 1997 The objective of this study was to investigate the influence of food on the bioavailability of omeprazole (20 mg) given as an enteric-coated tablet under repeated dose
ABR Thomson +5 more
doaj +1 more source
Preformulation and preliminary formulation studies of mesalazine gastro-resistant tablets [PDF]
Romanian Journal of Pharmaceutical Practice, 2020 Mesalamine, 5-aminosalicylic acid or mesalazine is the standard therapy of inflammatory bowel disease. A small number of pharmaceutical dosage forms with mesalazine are on the market.
Adriana Aurelia Chiş +5 more
doaj +1 more source
Uji Bioavailabilitas Tablet Floating Aspirin [PDF]
, 2017 Aspirin is a non-steroidal anti-inflammatory drug with potential as antiplatelet for stroke prophylaxis. Several approaches of aspirin formulations in various dosage forms have been performed.
Fudholi, Achmad +3 more
core +3 more sources
In vitro dissolution of proton-pump inhibitor products intended for paediatric and geriatric use in physiological bicarbonate buffer [PDF]
, 2015 Peer reviewedFinal Accepted ...
Liu, Fang, Shokrollahi, Honaz
core +1 more source
In Vivo Evaluation of a Gastroretentive Drug Delivery System Based on Enteric-Coated Floating Tablets [PDF]
, 2015 Floating dosage forms are supposed to exhibit an enhanced gastric residence time. Their development is challenging as the prediction of the retention potential in humans based on in vitro studies and animal models is difficult.
Alles, Rainer +4 more
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A NOVEL APPROACH IN DESIGNING ENTERIC-COATED ANTIPLATELET DRUG FOR BYPASSING STOMACH AND GASTRIC IRRITATION [PDF]
, 2020 Objective: The innovative approach in this investigation is making an enteric-coated acetylsalicylic acid (ASA) for antiplatelet activity using a novel excipient. Methods: A novel methodology used in making ASA tablets for tackling the stomach irritation
CHANDRA SEKHAR, KOTHAPALLI BANOOTH +2 more
core +1 more source