An oral multiparticulate, modified-release, hydrocortisone replacement therapy that provides physiological cortisol exposure [PDF]
Objective It is not possible with current hydrocortisone replacement to mimic the diurnal cortisol profile in patients with adrenal insufficiency. Previous attempts with modified-release technology were unsuccessful.
Arlt +23 more
core +1 more source
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han +17 more
wiley +1 more source
Ameliorative Effects of Selenium-Containing Proteins and Peptides from Selenium-Enriched Cardamine L. against Ulcerative Colitis in Mice [PDF]
Objective: To assess the mitigative effects of plant-derived organic selenium on ulcerative colitis (UC). Methods: Selenium-containing proteins (SePro) and peptides (SePP) were prepared from natural selenium-enriched Cardamine L.
MENG Yao, HE Ziyan, LUO Ying, ZHANG Zhong, LI Jianke, YUAN Li
doaj +1 more source
Formulation study of duloxetine hydrochloride enteric-coated tablets
During storage, duloxetine hydrochloride may have an unexpected cross reaction with enteric coated acrylic resin, which may affect the product quality.
Jiang Guowei +4 more
doaj +1 more source
Review of pyronaridine anti-malarial properties and product characteristics. [PDF]
Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J +7 more
core +2 more sources
Two‐photon lithography (TPL) enables 3D magnetic nanostructures with unmatched freedom in geometry and material choice. Advances in voxel control, deposition, and functionalization open pathways to artificial spin ices, racetracks, microrobots, and a number of additional technological applications.
Joseph Askey +5 more
wiley +1 more source
Magnitude and Duration of Elevated Gastric pH in Patients Infected with Human Immunodeficiency Virus After Administration of Chewable, Dispersible, Buffered Didanosine Tablets [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90191/1/phco.24.16.1539.50959 ...
Carver, Peggy L. +4 more
core +1 more source
Single Solid‐State Ion Channels as Potentiometric Nanosensors
Single gold nanopores functionalized with mixed self‐assembled monolayers act as solid‐state ion channels for direct, selective potentiometric sensing of inorganic ions (Ag⁺). The design overcomes key miniaturization barriers of conventional ion‐selective electrodes by combining low resistivity with suppressed loss of active components, enabling robust
Gergely T. Solymosi +4 more
wiley +1 more source
Formulation and In-Vitro Evaluation of Enteric Coated Tablet Incorporating Rabeprazole [PDF]
The objective of the work is to try and assess the applicability and manufacturing possibilities to optimize an enteric coated tablet formulation containing Rabeprazole sodium as the drug aiming at the anti-acidity activity with desired drug release ...
Cheke, Rameshwar S. +2 more
core +2 more sources
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava +7 more
wiley +1 more source

