Results 11 to 20 of about 5,191 (294)

In vitro evaluation of mesalazine enteric-coated tablet dissolution by the reciprocating cylinder method [PDF]

open access: yesScientific Reports
Mesalazine formulations are first-line treatments for ulcerative colitis. However, the drug release mechanisms of currently available mesalazine formulations on the market vary, and different in vitro dissolution methods have been used to characterize ...
Jinxiang Wang   +4 more
doaj   +2 more sources

Development of pH-Sensitive Multiparticulates for Orally Disintegrating Tablets of Proton Pump Inhibitors: Physicochemical Characterization and Drug Release Studies [PDF]

open access: yesPharmaceutics
Background/Objectives: Enteric coating protects active pharmaceutical ingredients from gastric degradation, but conventional tablets may present swallowing difficulties in geriatric and pediatric patients.
Mahendra Singh   +4 more
doaj   +2 more sources

In Silico Evaluation of the Biopharmaceutical and Pharmacokinetic Behavior of Metronidazole from Coated Colonic Release Matrix Tablets [PDF]

open access: yesPharmaceutics
Background: Physiologically based biopharmaceutics modeling (PBBM) models can help to predict drug release and in vivo absorption behaviors. Colon drug delivery systems have gained interest over the past few years due to the advantages they provide in ...
Roberto Arévalo-Pérez   +2 more
doaj   +2 more sources

Case report: Alectinib-associated intestinal ulceration and colitis in a patient with non-small cell lung cancer and effective treatment with Mesalazine [PDF]

open access: yesPathology and Oncology Research
BackgroundAlectinib is effective in extending the survival of patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) and generally has manageable side effects.
Zijian Qiu, Fei Ke, Xiaoping Zhu
doaj   +2 more sources

Modulation of mesalamine release from enteric-coated matrix tablets using natural polysaccharides for localized colonic delivery

open access: goldJournal of Applied Pharmaceutical Research
Background: Inflammatory bowel diseases (IBD) require effective colon-targeted drug delivery for improved therapeutic efficacy and minimized systemic side effects.
Shilpa Sahu   +5 more
doaj   +3 more sources

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