Results 221 to 230 of about 5,191 (294)

Pediatric Investigation Plans for seizure and epilepsy treatments: An analysis since the implementation of the European Pediatric Regulation in 2006

Epilepsia, EarlyView.
Abstract Objective A Pediatric Investigation Plan (PIP) implemented under the European Pediatric Regulation (EC No. 1901/2006) aims to ensure early and systematic evaluation of medicines for children. We analyze PIPs for antiseizure medications (ASMs) submitted to the European Medicines Agency (EMA) since 2006, characterizing their content, focusing on
Valeria Agostini, Stéphane Auvin
wiley   +1 more source

Bioequivalence of a single dose of two palbociclib formulations in healthy Chinese subjects under fasting conditions: a two-period crossover study with rabeprazole pre-treatment. [PDF]

Front Pharmacol
Bai W, Shi S, Yin D, Guo C, Song H, Hu Y, Gao J, Qiu B, Zhang X, Bi L, Wu H, Dong Z.   +11 more
europepmc   +1 more source

Equine botulism

Equine Veterinary Journal, EarlyView.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik, Robert Whitlock, Amy Johnson   +2 more
wiley   +1 more source

Enteric Coating Enhances the Biopharmaceutical Performance of a Silica-Lipid Formulation of Abiraterone Acetate. [PDF]

Pharmaceutics
Taheri A, Almasri R, Wignall A, Feltrin F, Bremmell KE, Joyce P, Prestidge CA.   +6 more
europepmc   +1 more source

Efficacy and welfare effects of different forms of physical restraint for upper airway endoscopy of horses

Equine Veterinary Journal, EarlyView.
Abstract Background Physical restraint of horses for veterinary procedures is necessary to allow completion of tasks effectively and without injury to patient or personnel. Objectives To compare physiological effects and behavioural responses to four commonly used restraint techniques for upper respiratory tract (URT) endoscopy in unsedated horses ...
Claire O'Brien, Olivier Simon, Samantha H. Franklin, Gustavo Ferlini Agne, Sarah Weaver, Sharanne L. Raidal   +5 more
wiley   +1 more source

Medication Adjustment After Bariatric and Metabolic Surgery: A Review of Current Evidence and Clinical Practice Trends. [PDF]

J Metab Bariatr Surg
Park JH, Kim S, Seo HS, Song KY, Lee HH.
europepmc   +1 more source

Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells

The FEBS Journal, EarlyView.
Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari, Kathryn Volkening, Zahra Nayeri, Aysegul Yucel Polat, Neil Donison, Jacqueline Palik, Michael J. Strong   +6 more
wiley   +1 more source

Right posterior communicating artery aneurysm with multiple arterial stenoses and moyamoya disease: A case report. [PDF]

J Int Med Res
Liu J, Shi Z, Liu H, Wen G.
europepmc   +1 more source

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

The FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira, Solon Andrades da Rosa, Luiza Cherobini Pereira, Laura Boose de Mendonça, Juliete Scholl, Fabrício Figueiró, Thais Cardoso Bitencourt, Davi Piovesan Echevarria, João Luiz Aldinucci Buzzo, Jessica Boschini D'Agostin, Danieli Rosane Dallemole, Carolina Oliveira, Fernanda Simas, Fernanda Saez‐Calazans, Débora Santos‐Sousa, Guido Lenz, Eduardo C. Filippi‐Chiela   +16 more
wiley   +1 more source

Efficacy and safety of probiotics combined with bismuth-containing quadruple therapy for <i>Helicobacter pylori</i> eradication: a systematic review and meta-analysis. [PDF]

Front Microbiol
Zhou S, Yu Y, Tian J, Wang X, Zeng M, Song H.   +5 more
europepmc   +1 more source