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Tableting and stability evaluation of enteric-coated omeprazole pellets
European Journal of Pharmaceutics and Biopharmaceutics, 2004In this study, fluidized-bed manufactured enteric-coated omeprazole pellets were compressed into tablets. The stability of the pellets and those of compressed tablets were evaluated for remaining omeprazole and for degradation products under an accelerated stability protocol. The data were analyzed using the artificial neural network (ANN) and analysis
Murat, Türkoğlu +2 more
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Gastric retention of enteric‐coated aspirin tablets in beagle dogs
Journal of Veterinary Pharmacology and Therapeutics, 1990Nap, R.C., Breen, D.J., Lam, T.J.G.M. & de Bruyne, J.J. Gastric retention of enteric‐coated aspirin tablets in beagle dogs. J. vet. Pharmacol. Therap. 13, 148–153.Administration of acetylsalicyclic acid (ASA) in the dog may cause gastric mucosal damage. Enteric‐coated tablets protect the canine stomach during oral ASA medication.
Nap, R C +3 more
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Scandinavian Journal of Gastroenterology, 1989
We studied the gastrointestinal side effects of three formulations of naproxen in 18 healthy male volunteers. In a Latin-square design crossover study, the subjects received 500 mg naproxen twice daily for 7 days as plain tablets, enteric-coated tablets, or enteric-coated granules in capsules.
L, Aabakken +5 more
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We studied the gastrointestinal side effects of three formulations of naproxen in 18 healthy male volunteers. In a Latin-square design crossover study, the subjects received 500 mg naproxen twice daily for 7 days as plain tablets, enteric-coated tablets, or enteric-coated granules in capsules.
L, Aabakken +5 more
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Compression of enteric-coated pellets to disintegrating tablets
International Journal of Pharmaceutics, 1996Abstract Enteric-coated sucrose pellets containing a layer of bisacodyl beneath the coating were compressed into tablets on an instrumented single-punch machine using four different filler-binders for direct compression. Different copolymers based on polymethacrylates were applied as coatings.
Thomas E. Beckert +2 more
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Enteric coated naproxen tablets.
European journal of rheumatology and inflammation, 1995It is postulated that the gastroduodenal mucosal side effects of naproxen are partly based on topical toxicity. With enteric coated aspirin tablets as a model product, enteric coated naproxen formulations have been developed. The extent of absorption is the same for enteric coated and plain tablets.
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Gastrointestinal symptoms associated with enteric-coated sulfasalazine (Azulfidine EN tablets)
Modern Rheumatology, 2002Abstract To investigate both the incidence and the dosage used to treat gastrointestinal (GI) symptoms associated with enteric-coated sulfasalazine (Azulfidine EN, AZL) in patients with rheumatoid arthritis (RA), we studied the clinical history of 153 RA patients, and any available data on GI symptoms that might have been associated with AZL.
S, Okubo, K, Nakatani, K, Nishiya
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Tolerance of Didanosine as Enteric-Coated Capsules versus Buffered Tablets
AIDS Patient Care and STDs, 2004329 E Didanosine (ddI) is a nucleoside analogue that competitively inhibits the HIV reverse transcriptase enzyme. The lability of the molecule in acid milieu reduces its bioavailability to 10% when administered orally.1 A first approach to overcome this limitation was the formulation of ddI as buffered tablets, so that the absorption of the drug was ...
Pablo, Barreiro +4 more
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Absorption and Metabolism of Aspirin Administered in Enteric-Coated Tablets
JAMA: The Journal of the American Medical Association, 1965Variations in the absorption pattern of aspirin in enteric-coated tablets and in solution were compared between subjects and between doses in any one subject. Absorption of enteric-coated tablets was complete but the rate was extremely variable. On the other hand, administration of aspirin in solution was not only complete, but also yielded well ...
J R, LEONARDS, G, LEVY
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Disintegration Test for Enteric-Coated Tablets
Journal of Pharmaceutical Sciences, 1977P L, Madan, H, Eisen
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