Results 291 to 300 of about 31,411 (361)

Fructose‐Induced Impairment of Liver and Skeletal Muscle Metabolism Is Prevented by Administration of Shouchella clausii Spores by Preserving Mitochondrial Function and Insulin Sensitivity

open access: yesMolecular Nutrition &Food Research, EarlyView.
S. clausii SF174 spores were effective in preventing the onset of low‐grade inflammation and insulin resistance induced by fructose‐rich diet in young rats, preserving the mitochondria from changes in the respiratory capacity in both liver and skeletal muscle, maintaining unaltered the oxidative balance, thus counteracting the deleterious effects of ...
Angela Di Porzio   +7 more
wiley   +1 more source

Challenges and Innovative Strategies in 3D Printing of Natural Biomolecular Hydrogels

open access: yesNano Select, EarlyView.
ABSTRACT Natural biomolecules with excellent biocompatibility, degradability, and the ability to guide effective tissue regeneration are considered ideal materials for constructing tissue engineering hydrogel scaffolds. The employing of 3D printing technology facilitates the preparation of natural biomolecular‐based scaffold for specific morphological
Jiaqi Qiu, Shuo Ma, Xue Qu
wiley   +1 more source

Modeling and Simulation of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended‐Release and Immediate‐Release Formulations in Healthy Adults Using the Quantitative Systems Toxicology Software Platform DILIsym

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 4, Page 681-694, April 2025.
ABSTRACT Acetaminophen (APAP) has been formulated as immediate‐, modified‐, and extended‐release tablets (APAP‐IR, ‐MR, and ‐ER, respectively). However, there was concern that APAP‐MR previously available in Europe could form a bezoar after a large overdose, leading to delayed absorption and atypical pharmacokinetics (PK) compared to APAP‐IR, and that ...
James J. Beaudoin   +9 more
wiley   +1 more source

Intracellular Proteins Targeting with Bi‐Functionalized Magnetic Nanoparticles Following their Endosomal Escape

open access: yesSmall, Volume 21, Issue 13, April 2, 2025.
In this work, γ‐Fe2O3@SiO2 core–shell magnetic nanoparticles are functionalized with polyhistidine peptides triggering endosomal escape and antibodies targeting specific cytosolic proteins. Thanks to a smart design of the nanoparticles and of the functionalization strategy, 90% of the internalized nanoparticles are able to target the chosen proteins ...
Mélody Perret   +9 more
wiley   +1 more source

Additive Manufacturing of Organic Electrochemical Transistors: Methods, Device Architectures, and Emerging Applications

open access: yesSmall, Volume 21, Issue 11, March 19, 2025.
Organic electrochemical transistors (OECTs) are essential for bioelectronics, neuromorphics, and flexible electronics. This review examines additive manufacturing advances for OECTs, covering printing techniques, device architectures, and applications including biochemical sensing, neuromorphic, green bio‐electronics, self‐healable, and 4D electronics.
Roberto Granelli   +2 more
wiley   +1 more source

MOF‐Based Bioelectronic Supercapacitors

open access: yesSmall, Volume 21, Issue 15, April 16, 2025.
This study examines the structural and functional characteristics of MOF‐based bioelectronic supercapacitors, highlighting their excellent conductivity and biocompatibility. Strategies for synthesis and functionalization enhance overall device efficiency. Due to their diverse application potential, these materials are recognized as promising candidates
Begüm Sarac   +2 more
wiley   +1 more source

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