Alendronate Sodium as Enteric Coated Solid Lipid Nanoparticles; Preparation, Optimization, and In Vivo Evaluation to Enhance Its Oral Bioavailability. [PDF]
Treatment of osteoporosis with alendronate sodium has several challenges. The first challenge is the low bioavailability. The second main challenge is side effects, which include oesophageal ulceration.
Khaled Mohamed Hosny
doaj +2 more sources
Characterization of enteric-coated erythromycin tablets by Raman mapping and its pharmaceutical evaluation [PDF]
Enteric tablet coating thickness is a critical quality attribute of the coating process that can affect dissolution behavior in vitro as well as release in vivo.
Wenbo Zou+3 more
doaj +2 more sources
In Vitro Evaluation of Enteric-Coated HPMC Capsules-Effect of Formulation Factors on Product Performance. [PDF]
A comparative study on different enteric-coated hard capsules was performed. The influence of different formulation factors like choice of enteric polymer, triethyl citrate (TEC) concentration (plasticizer), talc concentrations (anti-tacking agent), and ...
Fu M+4 more
europepmc +2 more sources
Bioequivalence of two esomeprazole magnesium enteric-coated formulations in healthy Chinese subjects. [PDF]
BACKGROUND The pharmacokinetics and bioequivalence of esomeprazole in healthy Chinese subjects and the effects of food on the pharmacokinetics have not been well studied. AIM To evaluate the pharmacokinetic characteristics of esomeprazole magnesium (Eso)
Liu ZZ, Ren Q, Zhou YN, Yang HM.
europepmc +2 more sources
Clinical Efficacy and Residue Depletion of 10% Enrofloxacin Enteric-Coated Granules in Pigs
A new, more palatable formulation of 10% enrofloxacin enteric-coated granules was investigated to evaluate the pharmacokinetic effect in plasma, the residue elimination in tissues and the clinical efficacy against Actinobacillus pleuropneumonia (APP) and
Zhixin Lei+14 more
doaj +2 more sources
Identification of Coating Materials for Enteric Coated Preparations
Enteric coating substances were tested in terms of disintegration time of the preparations. The samples used are 8 brands of multiple digestive enzyme capsules containing enteric coated granules and 5 of enteric coated granules (2 anti-inflammatory enzyme preparations and 1 each preparation of an antipyretic, kallidinogenase and ATP).
Yoshio Kanakubo+3 more
openalex +3 more sources
Surviving process and transit: Controlled freeze drying, storage and enteric coated capsules for targeted delivery of probiotic Lactobacillus acidophilus [PDF]
Viability loss of probiotics often occur during processing, storage and gastrointestinal transit. In this study, the viability of freeze-dried Lactobacillus acidophilus LA-5® was assessed after controlled freeze drying and storage at 4 °C and 25 °C over ...
Mansa Fredua-Agyeman
doaj +2 more sources
Efficacy of interventions with live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules in metabolic associated fatty liver disease patients: a meta-analysis of randomized controlled trials [PDF]
ObjectiveMetabolic associated fatty liver disease (MAFLD) is a common liver disease worldwide. However, effective therapies are still lacking. This meta-analysis aimed to compare the efficacy of interventions with or without live combined Bacillus ...
Yutong Wu, Hao Wu, Hang Yi
doaj +2 more sources
Enteric-coated insulin microparticles delivered by lipopeptides of iturin and surfactin
Surfactin, a lipopeptide produced by Bacillus species, has been used for the oral delivery of insulin. In this study, another lipopeptide of iturin was tested for its ability to orally delivery insulin alone or plus surfactin.
Xiaoying Xing+4 more
doaj +2 more sources
The main purpose of the present study was to prepare duloxetine hydrochloride (DXH) enteric-coated pellets using different enteric polymers. Three layers (drug-loaded layer, barrier layer, and enteric-coated layer) were applied to the inert core pellets,
Chen Kuang+6 more
doaj +2 more sources