Results 41 to 50 of about 1,680,432 (330)

Prevalence of Gastric and Small-Intestinal Mucosal Injury in Elderly Patients Taking Enteric-Coated Aspirin by Magnetically Controlled Capsule Endoscopy

Gastroenterology Research and Practice, 2019
Objective To investigate aspirin-related gastric and small-intestinal mucosal injury in elderly patients by magnetically controlled capsule endoscopy (MCCE).
F. Gao, Xue Chen, Jie Zhang
semanticscholar   +1 more source

Small-Intestine-Specific Delivery of Antidiabetic Extracts from Withania coagulans Using Polysaccharide-Based Enteric-Coated Nanoparticles

ACS Omega, 2019
Withania coagulans is an Indian medicinal herb, the natural extracts of which are purported to have health-benefiting properties. In this study, the extract was encapsulated in nature-derived polymers with the aim of enhancing its bioavailability.
Kaarunya Sampathkumar, S. Riyajan, Chiew Kei Tan, P. Demokritou, N. Chudapongse, Say Chye Joachim Loo   +5 more
semanticscholar   +1 more source

Rabeprazole sodium delayed-release multiparticulates: Effect of enteric coating layers on product performance

Journal of Advanced Pharmaceutical Technology & Research, 2011
Rabeprazole sodium is one of the most effective proton pump inhibitors (PPIs) used in antiulcer therapy. Like most other PPIs, owing to its acid-labile nature, the drug is formulated as enteric-coated dosage form.
Rakesh N Tirpude, Prashant K Puranik
doaj   +1 more source

Release property study on the novel divalproex sodium enteric-coated capsules

Saudi Pharmaceutical Journal, 2016
In the present study, a novel divalproex sodium (DS) enteric-coated capsule was prepared, and high performance liquid chromatography (HPLC) assay method for DS was developed.
Shuoye Yang, Xin Wang, Jiangsong Jia, Pengyuan Li   +3 more
doaj   +1 more source

Effects of Yunnan Baiyao retention enema combined with mesalazine enteric-coated tablets and bifidobacterium triple viable capsules for treating ulcerative colitis

结直肠肛门外科, 2022
[Objectives] To determine the effects of Yunnan Baiyao retention enema combined with mesalazine enteric-coated tablets and bifidobacterium triple viable capsules for treating ulcerative colitis (UC).
Liu Junjie, Gao Jian, Li Shuling
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Factors Contributing to Drug Release From Enteric-Coated Omeprazole Capsules: An In Vitro and In Vivo Pharmacokinetic Study and IVIVC Evaluation in Beagle Dogs

Dose-Response, 2020
This study was performed to explore factors influencing the release of the proton pump inhibitor omeprazole from enteric-coated capsules in vitro and absorption in vivo in beagle dogs.
Cheng Cui, Jiabei Sun, Xueqing Wang, Zhenxi Yu, Yaqin Shi   +4 more
doaj   +1 more source

Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation

Pharmaceutics, 2023
Oral delivery of peptides and biological molecules promises significant benefits to patients as an alternative to daily injections, but the development of these formulations is challenging due to their low bioavailability and high pharmacokinetic ...
Puneet Tyagi, Chandresh Patel, Kimberly Gibson, Fiona MacDougall, Sergei Y. Pechenov, Sarah Will, Jefferson Revell, Yue Huang, Anton I. Rosenbaum, Kemal Balic, Umar Maharoof, Joseph Grimsby, J. Anand Subramony   +12 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source