Results 41 to 50 of about 1,671,005 (331)

Release property study on the novel divalproex sodium enteric-coated capsules

Saudi Pharmaceutical Journal, 2016
In the present study, a novel divalproex sodium (DS) enteric-coated capsule was prepared, and high performance liquid chromatography (HPLC) assay method for DS was developed.
Shuoye Yang, Xin Wang, Jiangsong Jia, Pengyuan Li   +3 more
doaj   +1 more source

Effects of Yunnan Baiyao retention enema combined with mesalazine enteric-coated tablets and bifidobacterium triple viable capsules for treating ulcerative colitis

结直肠肛门外科, 2022
[Objectives] To determine the effects of Yunnan Baiyao retention enema combined with mesalazine enteric-coated tablets and bifidobacterium triple viable capsules for treating ulcerative colitis (UC).
Liu Junjie, Gao Jian, Li Shuling
doaj   +1 more source

Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation

Pharmaceutics, 2023
Oral delivery of peptides and biological molecules promises significant benefits to patients as an alternative to daily injections, but the development of these formulations is challenging due to their low bioavailability and high pharmacokinetic ...
Puneet Tyagi, Chandresh Patel, Kimberly Gibson, Fiona MacDougall, Sergei Y. Pechenov, Sarah Will, Jefferson Revell, Yue Huang, Anton I. Rosenbaum, Kemal Balic, Umar Maharoof, Joseph Grimsby, J. Anand Subramony   +12 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Preparation of Enteric Coated Pellets Containing Lansoprazole Using Extrusion/Spheronization Technique [PDF]

Trends in Pharmaceutical Sciences, 2016
Lansoprazole degrades rapidly in an aqueous solution at low pH values. Degradation rate increases at pH values below 4 .The aim of this study was development of enteric coated pellets containing Lansoprazole by an extrusion/ spheronization technique ...
Tavakol Heidari Shayesteh, Mina Abbasnia, Reza Mahjub   +2 more
doaj   +2 more sources

Enteric coated microspheres of pancreatin in the treatment of cystic fibrosis: comparison with a standard enteric coated preparation. [PDF]

Thorax, 1987
In an open, randomised crossover study enteric coated microspheres of pancreatin were compared with a standard preparation of enteric coated pancreatin over two consecutive 28 day treatment periods in 23 adults with steatorrhoea due to cystic fibrosis. Lipase intake was equal to the patients' previous requirements and was the same during the two months.
M E Hodson, J C Batten, I Skypala, R J Stead   +3 more
openaire   +3 more sources