Optimisation of the Manufacturing Process of Organic-Solvent-Free Omeprazole Enteric Pellets for the Paediatric Population: Full Factorial Design. [PDF]
Liquid formulations are mostly used in the paediatric population. However, with certain active pharmaceutical ingredients (APIs), it is very difficult to guarantee quality and stability; this is the case, for example, with omeprazole.
Rouaz-El-Hajoui K+9 more
europepmc +4 more sources
Surface Engineering Methods for Powder Bed Printed Tablets to Optimize External Smoothness and Facilitate the Application of Different Coatings [PDF]
In a previous attempt to achieve ileo-colonic targeting of bovine intestinal alkaline phosphatase (BIAP), we applied a pH-dependent coating, the ColoPulse coating, directly on powder bed printed (PBP) tablets.
Khanh T. T. Nguyen+6 more
doaj +3 more sources
Solid lipid nanoparticles with enteric coating for improving stability, palatability, and oral bioavailability of enrofloxacin. [PDF]
Chao Li,1 Kaixiang Zhou,1 Dongmei Chen,1,2 Wei Xu,1 Yanfei Tao,1 Yuanhu Pan,2 Kuiyu Meng,2 Muhammad Abu Bakr Shabbir,2 Qianying Liu,1 Lingli Huang,2 Shuyu Xie1 1National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for ...
Li C+10 more
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Characterization of enteric-coated erythromycin tablets by Raman mapping and its pharmaceutical evaluation. [PDF]
Enteric tablet coating thickness is a critical quality attribute of the coating process that can affect dissolution behavior in vitro as well as release in vivo.
Zou W, Liu W, Hu C.
europepmc +2 more sources
Exploring Immersion Coating as a Cost-Effective Method for Small-Scale Production of Enteric-Coated Gelatin Capsules. [PDF]
The coating process for solid dosage forms is widely used in the pharmaceutical industry but presents challenges for small-scale production, needed in personalized medicine and clinical or galenic settings. This study aimed to evaluate immersion coating,
Sabbatini B+4 more
europepmc +2 more sources
Extracellular matrix substrates differentially influence enteric glial cell homeostasis and immune reactivity. [PDF]
IntroductionEnteric glial cells are important players in the control of motility, intestinal barrier integrity and inflammation. During inflammation, they switch into a reactive phenotype enabling them to release inflammatory mediators, thereby shaping ...
Schneider L+3 more
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Preparation and Characterization of a Novel Aqueous Dispersion for Enteric Coating of Pantoprazole Sodium Pellets [PDF]
The purpose of this work was to investigate a novel aqueous dispersion (Eudragit® L100-55) f or e nteric c oating o f drugs. Three different casting solutions, Eudragit® L100-55 aqueous dispersion, Eudragit® L 100-55 o rganic s olution, and Eudragit ...
Han Min+4 more
doaj +3 more sources
Gastric-resistant isoniazid pellets reduced degradation of rifampicin in acidic medium [PDF]
Isoniazid and rifampicin are considered the first-line medication for preventing and treating tuberculosis. Rifampicin is degraded in the stomach acidic environment, especially when combined with isoniazid, factor contributing to treatment failure.
Fátima Duarte Freire+5 more
doaj +10 more sources
IgG-seq identifies immune-reactive enteric bacteria in Crohn's disease with spondyloarthritis. [PDF]
Joint inflammation is the most common extraintestinal manifestation of Crohn’s disease (CD). Although alterations in the enteric microbiota are described in CD with spondyloarthritis (CD-SpA), it is not known whether distinct taxa serve as markers for ...
Maldarelli GA+7 more
europepmc +2 more sources
Rabeprazole sodium is one of the most effective proton pump inhibitors (PPIs) used in antiulcer therapy. Like most other PPIs, owing to its acid-labile nature, the drug is formulated as enteric-coated dosage form.
Tirpude RN, Puranik PK.
europepmc +2 more sources