Results 91 to 100 of about 1,761,926 (341)
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
Dynamic interactions of a conserved enterotoxigenic Escherichia coli adhesin with intestinal mucins govern epithelium engagement and toxin delivery [PDF]
, 2016 At present, there is no vaccine for enterotoxigenic Escherichia coli (ETEC), an important cause of diarrheal illness. Nevertheless, recent microbial pathogenesis studies have identified a number of molecules produced by ETEC that contribute to its ...
Bhullar, Kirandeep +7 more
core +2 more sources
Robotic Pill for Biomarker and Fluid Sampling in the Gastrointestinal Tract
Advanced Intelligent Systems, 2022 Developing on‐site biomarker enrichment platforms could help to improve the diagnosis of gastrointestinal (GI) tract diseases at early stages. Medical procedures, such as colonoscopies and imaging techniques, are used to diagnose a disease, but are not ...
Fernando Soto +6 more
doaj +1 more source
The permeability of enteric coatings and the dissolution rates of coated tablets
Journal of Pharmacy and Pharmacology, 1982 Abstract The effect of an increasing concentration of plasticizer and pigment on the permeability to both water vapour and simulated gastric juice of cellulose acetate phthalate and polyvinyl acetate phthalate has been evaluated. There were significant differences between the permeability coefficients of each polymer, particularly with ...
S C Porter, K Ridgway
openaire +2 more sources
Characterization of ribosome heterogeneity during endothelial to hematopoietic transition
FEBS Open Bio, EarlyView.The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian +4 more
wiley +1 more source
Protection of dried probiotic bacteria from bile using bile adsorbent resins [PDF]
, 2014 Enteric coated oral tablets or capsules can deliver dried live cells directly into the intestine. Previously, we found that a live attenuated bacterial vaccine acquired sensitivity to intestinal bile when dried, raising the possibility that although ...
Alexander D. Edwards +19 more
core +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Impact of food, alcohol and pH on modified-release hydrocortisone developed to treat congenital adrenal hyperplasia. [PDF]
, 2017 BACKGROUND: We developed a modified-release hydrocortisone, Chronocort®, to replace the cortisol rhythm in patients with congenital adrenal hyperplasia.
Karunasena, N. +4 more
core +1 more source