The taste-masking of bitter-tasting active pharmaceutical ingredients is key to ensuring patient compliance when producing oral pharmaceutical formulations. This is generally achieved via the incorporation of pH-responsive, reverse enteric polymers, that
Kyle Brewer, Anton Blencowe
doaj +1 more source
Wet granulation method was used instead of conventional pan coating or fluidized –bed coating technique to prepare enteric-coated diclofenac sodium granules, using ethanolic solution of EudragitTM L100 as coating, binding and granulating agent ...
Eman B. H. Al-Khedairy
doaj +3 more sources
Rugotaxis: Droplet motion without external energy supply [PDF]
Nano-patterned substrates offer possibilities for controlling the motion of fluids without external energy supply in novel technologies in microfluidics, coatings, etc. Here, we report on the rugotaxial motion of droplets on wrinkled substrates with gradient in the wavelength of the wrinkles by exploring a broad range of parameters, such as amplitude ...
arxiv +1 more source
Absorption of enteric and non‐enteric coated prednisolone tablets. [PDF]
1. Relative rates of absorption of enteric and non‐enteric preparations of prednisolone were measured in five renal transplant recipients. 2. The absorption of the enteric coated preparation is delayed and the peak plasma concentration is much lower than that attained using the same dose of the uncoated material. 3.
B Hulme, R Rault, V. H. T. James
openaire +2 more sources
Clinical utility of cerebrospinal fluid biomarkers measured by LUMIPULSE® system
Abstract Objectives Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are well‐established in research settings, but their use in routine clinical practice remains a largely unexploited potential. Here, we examined the relationship between CSF biomarkers, measured by a fully automated immunoassay platform, and brain β‐amyloid (Aβ ...
Hisashi Nojima+9 more
wiley +1 more source
Optimal protection of stabilised dry live bacteria from bile toxicity in oral dosage forms by bile acid adsorbent resins [PDF]
We previously found that dried live bacteria of a vaccine strain can be temporarily sensitive to bile acids and suggested that Bile Adsorbing Resins (BAR) can be used in oral vaccine tablets to protect dried bacteria from intestinal bile. Here, we report
Chatterjee, Pratichi+4 more
core +1 more source
Optimasi Formula Tablet Salut Enterik Natrium Diklofenak dengan Bahan Penyalut Kollicoat 30 D [PDF]
Diclofenac sodium is an analgetic and antiinflammation drug and commonly used by oral administration. Because of it’s side effects that can cause stomach irritation, nausea and vomiting, it’s made in the form of enteric-coated.
Yunarto, Nanang
core +2 more sources
Water dispersible microbicidal cellulose acetate phthalate film [PDF]
BACKGROUND: Cellulose acetate phthalate (CAP) has been used for several decades in the pharmaceutical industry for enteric film coating of oral tablets and capsules.
A Robert Neurath+57 more
core +2 more sources
Modelling the Effect of Process Parameters on the Wet Extrusion and Spheronisation of High-Loaded Nicotinamide Pellets Using a Quality by Design Approach [PDF]
Open access articleThe aim of the present study was to develop an alternative process to spray granulation in order to prepare high loaded spherical nicotinamide (NAM) pellets by wet extrusion and spheronisation.
Keppler, Julia K+4 more
core +2 more sources
Angular resolved light scattering from micron-sized colloidal assemblies [PDF]
Disordered dielectrics with structural correlations on length scales comparable to visible light wavelengths exhibit complex optical properties. Such materials exist in nature, leading to beautiful structural non-iridescent color, and they are also increasingly used as building blocks for optical materials and coatings.
arxiv +1 more source